• Exploring risk and resilient profiles for functional impairment and baseline predictors in a 2-year follow-up first-episode psychosis cohort using latent class growth analysis

  Salagre, Estela; Bergé Baquero, Daniel; Bernardo, Miguel; PEPs Group (MDPI, 2020)

  Being able to predict functional outcomes after First-Episode Psychosis (FEP) is a major goal in psychiatry. Thus, we aimed to identify trajectories of psychosocial functioning in a FEP cohort followed-up for 2 years in ...
• Clinical profiles in renal patients with COVID-19

  Arenas Jiménez, María Dolores; Crespo Barrio, Marta; Pérez-Sáez, María José; Collado Nieto, Silvia; Redondo Pachón, María Dolores; Llinàs-Mallol, Laura; Montero, Maria Milagro; Villar García, Judit; Arias Cabrales, Carlos Enrique; Barbosa Puig, Francisco; Buxeda, Anna; Burballa Tarrega, Carla Cristina; Sans Atxer, Laia; Vázquez, Susana; Oliveras, Anna; Mir, Marisa; Outón González, Sara; Galceran Herrera, Isabel; Solà Porta, Eulàlia; Sierra Ochoa, Adriana; Barrios Barrera, Clara; Rodriguez García, Eva; Cao Baduell, Higinio (MDPI, 2020)

  The COVID-19 pandemic has led to frequent referrals to the emergency department on suspicion of this infection in maintenance hemodialysis (MHD) and kidney transplant (KT) patients. We aimed to describe their clinical ...
• Cancer signaling transcriptome is upregulated in type 2 diabetes mellitus

  Almanza-Aguilera, Enrique; Hernáez, Álvaro; Corella, Dolores; Sanllorente Melenchón, Albert; Ros, Emilio; Portolés, Olga; Valussi, Julieta; Estruch, Ramón; Coltell, Oscar; Subirana Cachinero, Isaac; Canudas i Puig, Sílvia; Razquin, Cristina; Blanchart, Gemma; Nonell Mazelón, Lara; Fitó Colomer, Montserrat; Castañer, Olga (MDPI, 2020)

  We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based transcriptome analysis ...
• Alcohol induced depression: clinical, biological and genetic features

  Farré Martínez, Adriana; Tirado Muñoz, Judit; Spataro, Nino; Alías Ferri, María; Torrens, Marta; Fonseca Casals, Francina, 1972- (MDPI, 2020)

  Background: In clinical practice, there is the need to have clinical and biological markers to identify induced depression. The objective was to investigate clinical, biological and genetic differences between Primary Major ...
• Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study

  Benaiges Foix, David; Bisbe Maria; Pedro-Botet, Juan Carlo; Vargas-Machuca, Aleix de; Ramón Moros, José Manuel; Pera Roman, Manuel Ramón; Villatoro Moreno, Montserrat; Fontane Francia, Laia; Julià, Helena; Climent Biescas, Elisenda; Castañer, Olga; Flores-Le-Roux, Juana Antonia; Goday Arno, Alberto (MDPI, 2020)

  To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery ...
• Cannabidiol modulates the motivational and anxiety-like effects of 3,4-methylenedioxypyrovalerone (MDPV) in mice

  Alegre Zurano, Laia; López Arnau, Raúl; Luján Pérez, Miguel Ángel, 1991-; Camarasa, Jordi; Valverde Granados, Olga (MDPI, 2021)

  3,4-Methylenedioxypyrovalerone (MDPV) is a new psychoactive substance (NPS) and the most widespread and life-threatening synthetic cathinone of the "bath salts". Preclinical research has proven the cocaine-like psychostimulant ...
• Phenotypic clustering in non-cystic fibrosis bronchiectasis patients: the role of eosinophils in disease severity

  Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; García Ojalvo, Jordi; Barreiro Portela, Esther (MDPI, 2021)

  Whether high blood eosinophil counts may define a better phenotype in bronchiectasis patients, as shown in chronic obstructive pulmonary disease (COPD), remains to be investigated. Differential phenotypic characteristics ...
• Co-treatment with verapamil and curcumin attenuates the behavioral alterations observed in Williams-Beuren syndrome mice by regulation of MAPK pathway and microglia overexpression

  Ortiz Romero, Paula, 1994-; González-Simón, Alejandro; Egea, Gustavo; Pérez Jurado, Luis Alberto; Campuzano Uceda, María Victoria (Frontiers, 2021)

  Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by a distinctive cognitive phenotype for which there are currently no effective treatments. We investigated the progression of behavioral ...
• FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease

  Garcia-Recio, Susana; Albanell Mestres, Joan; Perou, Charles M. (American Society for Clinical Investigation, 2020)

  Mechanisms driving tumor progression from less aggressive subtypes to more aggressive states represent key targets for therapy. We identified a subset of luminal A primary breast tumors that give rise to HER2-enriched ...
• Effect of bariatric surgery on cardiac structure and function in obese patients: role of the renin-angiotensin system

  Oliveras, Anna; Molina Ferragut, Luis; Goday Arno, Alberto; Sans Atxer, Laia; Riera, Marta; Vázquez, Susana; Benaiges Foix, David; Granados, Ana Marina; Ramon, Jose Manuel; Pascual Santos, Julio (Wiley, 2021)

  Echocardiographic alterations have been described in obesity, but their modifications after bariatric surgery (BS) and mechanisms are little known, mostly in normotensive patients. We aimed to analyze cardiac changes 1 ...
• Intraoperative bacterial contamination and activity of different antimicrobial prophylaxis regimens in primary knee and hip replacement

  Rivera, Alba; Sánchez, Alba; Luque Pardos, Sònia; Mur, Isabel; Puig, Lluís; Puig, Lluís; Crusi, Xavier; González, José Carlos; Sorli Redó, M. Luisa; González, Aránzazu; Horcajada Gallego, Juan Pablo; Navarro, Ferran; Benito, Natividad (MDPI, 2020)

  Surgical antimicrobial prophylaxis (SAP) is important for the prevention of prosthetic joint infections (PJIs) and must be effective against the microorganisms most likely to contaminate the surgical site. Our aim was to ...
• Prevalence and age patterns of depression in the United Kingdom. A population-based study

  Arias-de la Torre, Jorge; Vilagut Saiz, Gemma, 1975-; Ronaldson, Amy; Dregan, Alex; Ricci-Cabello, Ignacio; Hatch, Stephani L.; Serrano-Blanco, Antoni; Valderas Martínez, José María; Hotopf, Matthew; Alonso Caballero, Jordi (Elsevier, 2021)

  Methods: A representative sample of the UK population (n=17,152) from the European Health Interview Survey of 2014 was included in the analyses. The Patient Health Questionnaire (PHQ-8) was used to assess the prevalence ...
• Effects of the COVID-19 pandemic and lockdown in Spain: comparison between community controls and patients with a psychiatric disorder

  Solé, Brisa; Verdolini, Norma; Amoretti, Silvia; Montejo, Laura; Rosa, Adriane R.; Hogg, Bridget; García-Rizo, Clemente; Mezquida, Gisela; Bernardo, Miquel; Martínez-Aran, Anabel; Vieta, Eduard; Torrent, Carla (Elsevier, 2021)

  Background: The aim of this study was to evaluate potential differences about the effects of the COVID-19 pandemic and lockdown between community controls (CC) and patients with a mental illness (MI) in a Spanish population ...
• Short stature with low insulin-like growth factor 1 availability due to pregnancy-associated plasma protein A2 deficiency in a Saudi family

  Babiker, Amir; Al Noaim, Khalid; Al Swaid, Abdulrahman; Alfadhel, Majid; Deeb, Asma; Martín Rivada, Álvaro; Barrios, Vicente; Pérez Jurado, Luis Alberto; Alfares, Ahmed; Al Alwan, Ibrahim; Argente, Jesús (Wiley, 2021)

  In 2016 a new syndrome with postnatal short stature and low IGF1 bioavailability caused by biallelic loss-of-function mutations in the gene encoding the metalloproteinase pregnancy-associated plasma protein A2 (PAPP-A2) ...
• Association between informal employment and mortality rate by welfare regime in Latin America and the Caribbean: an ecological study

  Silva-Peñaherrera, Michael, 1984-; López Ruiz, María, 1982-; Merino Salazar, Pamela Alexandra, 1978-; Gómez García, Antonio Ramón; Benavides, Fernando G. (Fernando García) (BMJ Publishing Group, 2021)

  Objective: We aimed to estimate the association between informal employment and mortality in Latin America and the Caribbean (LAC) by comparing welfare state regimes. Design: Ecological study using time-series cross-sectional ...
• A molecular sensor for cholesterol in the human serotonin 1A receptor

  Kumar, G Aditya; Sarkar, Parijat; Stepniewski, Tomasz Maciej, 1988-; Jafurulla, Md; Singh, Shishu Pal; Selent, Jana; Chattopadhyay, Amitabha (American Association for the Advancement of Science (AAAS), 2021)

  The function of several G protein-coupled receptors (GPCRs) exhibits cholesterol sensitivity. Cholesterol sensitivity of GPCRs could be attributed to specific sequence and structural features, such as the cholesterol ...
• Impact of the implementation of best practice guidelines on nurse's evidence-based practice and on nurses' work environment: research protocol

  Esteban-Sepúlveda, Silvia; Sesé-Abad, Albert; Lacueva-Pérez, Laia; Domingo-Pozo, Manuela; Alonso-Fernandez, Sergio; Aquilue-Ballarín, Marta; Barceló-Martínez, Ana Isabel; Cristóbal-Domínguez, Estíbaliz; Bujalance-Hoyos, Jesús; Dossantos-Sanchez, Consuelo; Pascual-Pascual, Manuel Angel; Garcia-Arteaga, Elisabeth; Galisteo-Giménez, Maria; Mas-Dalmau, Gemma; Heredia-Reina, Maria Pilar; Roca-Marti, Silvia; Pérez Riart, María; Albornos-Muñoz, Laura; González-María, Esther; Fernández-Domínguez, Juan C. (Wiley, 2021)

  Aim: To determine the impact of the Best Practice Spotlight Organization® initiative on nurses' perception of their work environment and their attitudes to evidence-based practice. Design: Quasi-experimental, multicentre ...
• Normative data for impact microindentation for Australian men: cross-sectional data from the geelong osteoporosis study

  Rufus-Membere, Pamela; Holloway-Kew, Kara L.; Kotowicz, Mark A.; Diez Pérez, Adolfo; Pasco, Julie A. (Wiley, 2020)

  Impact microindentation (IMI) is a novel technique for assessing the bone material strength index (BMSi) in vivo. However, no studies have presented normative data for BMSi. The aim of this study was to develop such normative ...
• EGFR and KRAS mutations in lung parenchyma of subjects with EGFR/KRAS wild-type lung adenocarcinoma

  Chalela Rengifo, Roberto José, 1985-; González-García, José Gregorio; Khilzi, Karys; Curull Serrano, Víctor; Sánchez Font, Albert; Longarón Rozalen, Raquel; Rodrigo Calvo, Maria Teresa; Martín-Ontiyuelo, Clara; Gea Guiral, Joaquim; Bellosillo Paricio, Beatriz (Frontiers, 2021)

  The acquisition of driver mutations in non-tumoral cells appears to be very important during the carcinogenesis of adenocarcinoma (ADC). Recent studies suggest that cancer-related mutations may not necessarily be present ...
• Metabolic, affective and neurocognitive characterization of metabolic syndrome patients with and without food addiction. Implications for weight progression

  Camacho Barcia, Lucía; Munguía, Lucero; Lucas, Ignacio; Torre Fornell, Rafael de la; Salas Salvadó, Jordi; Pintó Sala, Xavier; Corella, Dolores; Granero, Roser; Jiménez Murcia, Susana; González Monje, Inmaculada; Esteve Luque, Virginia; Cuenca Royo, Aida Ma, 1981-; Gómez Martínez, Carlos; Paz-Graniel, Indira; Forcano, Laura; Fernández Aranda, Fernando (MDPI, 2021)

  According to the food addiction (FA) model, the consumption of certain types of food could be potentially addictive and can lead to changes in intake regulation. We aimed to describe metabolic parameters, dietary ...

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