• Asma leve y exacerbaciones de riesgo vital: ¿es hora de que demos un paso adelante?

  González-García, José Gregorio; Chalela Rengifo, Roberto José, 1985-; Carballo Martínez, Núria; Ausín Herrero, Pilar, 1974- (Elsevier, 2020)
• Impact of a community contraceptive counselling intervention on adolescent fertility rates: a quasi-experimental study

  Díez, Elia; López, María J.; Pérez, Glòria; García Subirats, Irene, 1982-; Nebot, Laia; Carreras Collado, Ramón; Villalbí, Joan R. (BioMed Central, 2020)

  Background: From 2000 to 2008, in urban areas in Spain, adolescent fertility and abortion rates underwent unprecedented increases, consecutive to intensive immigration from developing countries. To address unmet needs for ...
• Cannabis use induces distinctive proteomic alterations in olfactory neuroepithelial cells of schizophrenia patients

  Barrera Conde, Marta; Ausín, Karina; Lachén Montes, Mercedes; Fernández Irigoyen, Joaquín; Galindo Guarín, Liliana; Cuenca Royo, Aida Ma, 1981-; Fernández Avilés, Cristina; Pérez, Victor; Torre Fornell, Rafael de la; Santamaría, Enrique; Robledo, Patricia, 1958- (MDPI, 2021)

  A close epidemiological link has been reported between cannabis use and schizophrenia (SCZ). However, biochemical markers in living humans related to the impact of cannabis in this disease are still missing. Olfactory ...
• Complete genomic characterization of a new KLRC2 allele, NKG2C*03

  Asenjo, Judit; Muntasell i Castellví, Aura, 1972-; López-Botet, M. (Miguel); Moraru, Manuela; Vilches, Carlos (Wiley, 2021)
• B cells and tertiary lymphoid structures influence survival in lung cancer patients with resectable tumors

  Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Wang, Xuejie; Mateu Jiménez, Mercè, 1990-; Pijuan Andujar, Lara; Duran, Xavier; Qin, Liyun; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (MDPI, 2020)

  Immune profile of B and T cells and tertiary lymphoid structures (TLSs) may differ in tumors of lung cancer (LC) patients with/without chronic obstructive pulmonary disease (COPD), and may also influence patient survival. ...
• Belatacept in kidney transplant patients with systemic lupus erythematosus

  Carrión-Barberà, María Irene; Fajardo, Melissa; Danias, George; Tsapepas, Demetra; Gartshteyn, Yevgeniya; Fernández, Hilda; Askanase, Anca (BMJ Publishing Group, 2019)

  Objectives: Lupus nephritis (LN) requires renal replacement therapy in 10%-30% of patients. About 30% of these patients receive a kidney transplant. Belatacept is a second-generation, selective, T-cell co-stimulator blocker ...
• Seguridad renal de espironolactona en pacientes con hipertensión arterial resistente

  Galceran Herrera, Isabel; Vázquez, Susana; Duran Jordà, Xavier, 1974-; Outón González, Sara; Pascual Santos, Julio; Oliveras, Anna (Elsevier, 2020)

  Introducción La hipertensión arterial resistente (HTAR) supone un importante problema de salud de manejo complejo. Este trabajo evalúa los riesgos y beneficios de añadir espironolactona para tratar la HTAR. Material y ...
• Economic evaluations of screening strategies for the early detection of colorectal cancer in the average-risk population: a systematic literature review

  Mendivil, Joan; Appierto, Marilena; Aceituno, Susana; Comas Serrano, Mercè; Rué, Montserrat (Public Library of Science (PLoS), 2019)

  Background: Colorectal cancer (CRC) screening has proven effective in reducing CRC mortality. This study aimed to systematically review, and evaluate the reporting quality, of the economic evidence regarding CRC screening ...
• Increased PARP activity and DNA damage in NSCLC patients: the influence of COPD

  Tang, Jun; Curull Serrano, Víctor; Wang, Xuejie; Ampurdanés, Coral; Duran, Xavier; Pijuan Andujar, Lara; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Yélamos López, José; Barreiro Portela, Esther (MDPI, 2020)

  (1) Background: Lung cancer (LC) is a major leading cause of death worldwide. Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 are key players in cancer. We aimed to assess PARP-1 and PARP-2 expression and activity and DNA ...
• Prolonged immobilization exacerbates the loss of muscle mass and function induced by cancer-associated cachexia through enhanced proteolysis in mice

  Mañas García, Laura, 1991-; Penedo Vázquez, Antonio; López Postigo, Adrián; Deschrevel, Jorieke; Durán, Xavier; Barreiro Portela, Esther (MDPI, 2020)

  We hypothesized that in mice with lung cancer (LC)-induced cachexia, periods of immobilization of the hindlimb (7 and 15 days) may further aggravate the process of muscle mass loss and function. Mice were divided into seven ...
• Exploring the role of breast density on cancer prognosis among women attending population-based screening programmes

  Domingo Torrell, Laia; Sala Serra, Maria; Louro, Javier; Baré, Marisa; Barata, Teresa; Ferrer, Joana; Carmona-Garcia, Maria Carmen; Comas Serrano, Mercè; Castells, Xavier; Camiss Study Group (Hindawi, 2019)

  Background: Our aim was to assess the role of breast density on breast cancer mortality and recurrences, considering patient and tumour characteristics and the treatments received among women attending population-based ...
• Factores de riesgo asociados diferencialmente a la enfermedad de hígado graso no alcohólico en hombres y mujeres con síndrome metabólico

  Bullón Vela, María Vanessa; Abete, Itziar; Zulet, M. Angeles; Tur, J. Antoni; Pinto, Xavier; Corbella, Emili; Martínez-González, Miguel A.; Corella, Dolores; Macías-González, Manuel; Tinahones Madueño, Francisco José; Fitó Colomer, Montserrat; Estruch, Ramón; Ros, Emilio; Salas-Salvadó, Jordi; Daimiel, Lidia; Martínez, José Alfredo (Grupo Aran, 2020)

  Introducción: el hígado graso no alcohólico (HGNA) es una enfermedad hepática crónica más prevalente en los países occidentales. Objetivos: evaluar factores de riesgo asociados a HGNA en hombres y mujeres diagnosticados ...
• Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome

  Starbuck, John M.; Llambrich, Sergi; González, Rubén; Albaigès, Júlia; Sarlé, Anna; Wouters, Jens; González, Alejandro; Sevillano, Xavier; Sharpe, James; Torre Fornell, Rafael de la; Dierssen, Mara; Velde, Greetje Vande; Martínez Abadías, Neus (Nature Research, 2021)

  Trisomy of human chromosome 21 (Down syndrome, DS) alters development of multiple organ systems, including the face and underlying skeleton. Besides causing stigmata, these facial dysmorphologies can impair vital functions ...
• Teleost IgD + IgM - B cells mount clonally expanded and mildly mutated intestinal IgD responses in the absence of lymphoid follicles

  Perdiguero, Pedro; Martín-Martín, Alba; Benedicenti, Ottavia; Díaz-Rosales, Patricia; Morel, Esther; Muñoz-Atienza, Estefanía; García-Flores, Mónica; Simón, Rocío; Soleto, Irene; Cerutti, Andrea, 1965-; Tafalla, Carolina (Elsevier, 2019)

  Immunoglobulin D (IgD) is an ancient antibody with dual membrane-bound and fluid-phase antigen receptor functions. The biology of secreted IgD remains elusive. Here, we demonstrate that teleost IgD+IgM- plasmablasts ...
• Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

  Galmes-Panades, Aina M.; Schröder, Helmut, 1958-; Castañer, Olga; Pérez-Vega, Karla Alejandra; Fitó Colomer, Montserrat; Romaguera Bosch, Dora (BioMed Central, 2019)

  Background: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating ...
• MicroRNA-33b suppresses epithelial-mesenchymal transition repressing the MYC-EZH2 pathway in HER2+ breast carcinoma

  Pattanayak, Birlipta; Garrido Cano, Iris; Adam-Artigues, Anna; Tormo, Eduardo; Pineda, Begoña; Cabello, Paula; Alonso, Elisa; Bermejo, Begoña; Hernando, Cristina; Martínez, María Teresa; Rovira, Ana; Albanell Mestres, Joan; Rojo, Federico; Burgués, Octavio; Cejalvo, Juan M.; Lluch, Ana; Eroles, Pilar (Frontiers, 2020)

  Downregulation of miR-33b has been documented in many types of cancers and is being involved in proliferation, migration, and epithelial-mesenchymal transition (EMT). Furthermore, the enhancer of zeste homolog 2-gene (EZH2) ...
• Heterologous microProtein expression identifies LITTLE NINJA, a dominant regulator of jasmonic acid signaling

  Hong, Shin-Young; Sun, Bin; Straub, Daniel; Blaakmeer, Anko; Mineri, Lorenzo; Koch, Jonas; Brinch-Pedersen, Henrik; Holme, Inger B.; Burow, Meike; Lyngs Jørgensen, Hans Jørgen; Albà Soler, Mar; Wenkel, Stephan (National Academy of Sciences, 2020)

  MicroProteins are small, often single-domain proteins that are sequence-related to larger, often multidomain proteins. Here, we used a combination of comparative genomics and heterologous synthetic misexpression to isolate ...
• DSM-5 Internet gaming disorder among a sample of Mexican first-year college students

  Borges, Guilherme; Orozco, Ricardo; Benjet, Corina; Martínez Martínez, Kalina I.; Vargas Contreras, Eunice; Jiménez Pérez, Ana Lucía; Peláez Cedrés, Alvaro Julio; Hernández Uribe, Praxedis Cristina; Covarrubias Díaz Couder, María Anabell; Gutiérrez-García, Raúl A.; Quevedo Chavez, Guillermo E.; Albor, Yesica; Mendez, Enrique; Medina-Mora, María Elena; Mortier, Philippe; Rumpf, Hans-Juergen (Akadémiai Kiadó (AKJournals), 2019)

  Background and aims: DSM-5 includes Internet gaming disorder (IGD) as a condition for further study. While online and offline gaming may produce undesired negative effects on players, we know little about the nosology of ...
• Validation of cancer diagnoses in electronic health records: results irom The Information System For Research In Primary Care (SIDIAP) in northeast Spain

  Recalde, Martina; Manzano Salgado, Cyntia Beatriz, 1987-; Díaz, Yesika; Puente, Diana; García-Gil, Maria Del Mar; Marcos-Gragera, Rafael; Ribes-Puig, Josefa; Galceran, Jaume; Posso, Margarita; Macià, Francesc; Duarte Salles, Talita, 1985- (Editor de càrrega, 2019)

  Background: Electronic health records are becoming an increasingly valuable resource for epidemiology but their data quality needs to be quantified. We aimed to validate twenty-five types of incident cancer cases in the ...
• Evaluation of patellar contact pressure changes after static versus dynamic medial patellofemoral ligament reconstructions using a finite element model

  Sanchis-Alfonso, Vicente; Ginovart, Gerard; Alastruey-López, Diego; Montesinos-Berry, Erik; Monllau García, Juan Carlos; Alberich-Bayarri, Angel; Pérez, María Angeles (MDPI, 2019)

  Objectives: To evaluate the effect of various medial patellofemoral ligament (MPFL) fixation techniques on patellar pressure compared with the native knee. Methods: A finite element model of the patellofemoral joint ...

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