• Multimorbidity clusters among long-term breast cancer survivors in Spain: Results of the SURBCAN study

  Jansana Riera, Anna; Poblador-Plou, Beatriz; Gimeno-Miguel, Antonio; Lanzuela, Manuela; Prados-Torres, Alexandra; Domingo, Laia; Comas Serrano, Mercè; Sanz Cuesta, Teresa; Del Cura, Maria Isabel; Ibañez, Berta; Abizanda, Mercè; Duarte Salles, Talita, 1985-; Padilla-Ruiz, Maria; Redondo, Maximino; Castells, Xavier; Sala Serra, Maria; SURBCAN group (Wiley, 2021)

  The disease management of long-term breast cancer survivors (BCS) is hampered by the scarce knowledge of multimorbidity patterns. The aim of our study was to identify multimorbidity clusters among long-term BCS and assess ...
• Risk of breast cancer two years after a benign biopsy depends on the mammographic feature prompting recall

  Vernet-Tomás, Maria; Louro, Javier; Román, Marta; Saladié, Francina; Posso, Margarita; Prieto, Miguel; Vázquez, Ivonne; Baré, Marisa; Peñalva, Lupe; Vidal, Carmen; Bargalló, Xavier; Sánchez, Mar; Ferrer, Joana; Espinàs, Josep Alfons; Quintana, María Jesús; Rodríguez Arana, Ana Maria; Castells, Xavier; BELE Study Group (Elsevier, 2021)

  Objective: We aimed to explore whether the type of mammographic feature prompting a false-positive recall (FPR) during mammography screening influences the risk and timing of breast cancer diagnosis, particularly if assessed ...
• European Surveillance System on Contact Allergies (ESSCA): Characteristics of patients patch tested and diagnosed with irritant contact dermatitis

  Loman, Laura; Giménez Arnau, Anna Maria; ESSCA Working Group (Wiley, 2021)

  Background: Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or the cumulative exposure to various weaker physical and/or chemical irritants. Objectives: To describe the ...
• Reduced expansion of CD94/NKG2C + NK cells in chronic lymphocytic leukemia and CLL-like monoclonal B-cell lymphocytosis is not related to increased human cytomegalovirus seronegativity or NKG2C deletions

  Puiggros Metje, Anna Maria; Blanco Ares, Gonzalo, 1989-; Muntasell i Castellví, Aura, 1972-; Rodríguez-Rivera, María; Nonell Mazelón, Lara; Altadill, Mireia; Puigdecanet Riubugent, Eulàlia; Arnal, Magdalena; Calvo, Xavier; Gimeno, Eva; Abella Monreal, Eugenia; Abrisqueta, Pau; Bosch José, Francesc Xavier, 1947-; Yélamos López, José; Ferrer, Ana; López-Botet, M. (Miguel); Espinet Solà, Blanca (Wiley, 2021)

  Introduction: Dysregulated NK cell-mediated immune responses contribute to tumor evasion in chronic lymphocytic leukemia (CLL), although the NK cell compartment in CLL-like monoclonal B-cell lymphocytosis (MBL) is poorly ...
• Identification of the core chemical structure in SureChEMBL patents

  Falaguera, Maria J.; Mestres i López, Jordi (American Chemical Society (ACS), 2021)

  The SureChEMBL database provides open access to 17 million chemical entities mentioned in 14 million patents published since 1970. However, alongside with molecules covered by patent claims, the database is full of starting ...
• Deficient muscle regeneration potential in sarcopenic COPD patients: Role of satellite cells

  Sancho Muñoz, Antonio; Guitart, Maria; Rodríguez, Diego; Gea Guiral, Joaquim; Martínez-Llorens, Juana Mª; Barreiro Portela, Esther (Wiley, 2021)

  Sarcopenia is a major comorbidity in chronic obstructive pulmonary (COPD). Whether deficient muscle repair mechanisms and regeneration exist in the vastus lateralis (VL) of sarcopenic COPD remains debatable. In the VL of ...
• Perceived helpfulness of treatment for specific phobia: Findings from the World Mental Health Surveys

  de Vries, Ymkje Anna; Alonso Caballero, Jordi; WHO World Mental Health Survey Collaborators (Elsevier, 2021)

  Background: Although randomized trials show that specific phobia treatments can be effective, it is unclear whether patients experience treatment as helpful in clinical practice. We investigated this issue by assessing ...
• Ultra-high performance liquid chromatography-high resolution mass spectrometry and high-sensitivity gas chromatography-mass spectrometry screening of classic drugs and new psychoactive substances and metabolites in urine of consumers

  Marchei, Emilia; Ferri, Maria Alias; Torrens, Marta; Farré Albaladejo, Magí; Pacifici, Roberta; Pichini, Simona; Pellegrini, Manuela (MDPI, 2021)

  The use of the new psychoactive substances is continuously growing and the implementation of accurate and sensible analysis in biological matrices of users is relevant and fundamental for clinical and forensic purposes. ...
• Phenotypic and functional consequences of PLT binding to monocytes and its association with clinical features in SLE

  Mariscal, Anaís; Zamora, Carlos; Magallares, Berta; Salman-Monte, Tarek Carlos; Ortiz, Miguel A.; Díaz-Torné, Cesar; Castellví, Iván; Corominas, Héctor; Vidal, Silvia (MDPI, 2021)

  Platelets (PLTs) can modulate the immune system through the release of soluble mediators or through interaction with immune cells. Monocytes are the main immune cells that bind with PLTs, and this interaction is increased ...
• Metabolic signatures associated with severity in hospitalized COVID-19 patients

  Marín Corral, Judith; Rodríguez-Morató, Jose, 1987-; Gómez-Gómez, Àlex; Pascual Guàrdia, Sergi, 1979-; Muñoz-Bermúdez, Rosana; Salazar Degracia, Anna; Pérez-Terán, Purificación; Restrepo, Marcos I.; Khymenets, Olha, 1974-; Haro, Noemí; Masclans Enviz, Joan Ramon; Pozo Mendoza, Óscar J., 1975- (MDPI, 2021)

  The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the metabolic pathways that are altered early with viral infection and their association with disease severity is crucial to understand COVID-19 ...
• Both specific endothelial and proximal tubular Adam17 deletion protect against diabetic nephropathy

  Palau González, Vanesa; Nugraha, Bramasta; Benito, David; Pascual Santos, Julio; Emmert, Maximilian Y.; Hoerstrup, Simon P.; Riera, Marta; Soler, María José (MDPI, 2021)

  ADAM17 is a disintegrin and metalloproteinase capable of cleaving the ectodomains of a diverse variety of molecules including TNF-α, TGF-α, L-selectin, and ACE2. We have previously demonstrated that renal ADAM17 is upregulated ...
• Impact of the COVID-19 pandemic on tuberculosis management in Spain

  Aznar, María Luisa; Jové, Neus; Sánchez Martínez, Francisca; Sánchez Montalvá, Adrián (Elsevier, 2021)

  Background: The impact of COVID-19 on the diagnosis and management of tuberculosis (TB) patients is unknown. Methods: Participating centres completed a structured web-based survey regarding changes to TB patient management ...
• Clinical case report: endoluminal thermal ablation of main pancreatic duct for patients at high risk of postoperative pancreatic fistula after pancreaticoduodenectomy

  Ielpo, Benedetto; Pueyo Périz, Eva M.; Radosevic, Aleksandar; Andaluz, Anna; Berjano, Enrique J.; Grande Posa, Luís; Sánchez Velázquez, Patricia, 1985-; Burdío Pinilla, Fernando (Taylor & Francis, 2021)

  Purpose: Multiple attempts have been made to manage the pancreatic stump and the pancreatic duct in order to reduce the rate of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD), however ...
• Understanding how to improve the use of clinical coordination mechanisms between primary and secondary care doctors: clues from Catalonia

  Esteve Matalí, Laura; Vargas, Ingrid; Amigo, Franco; Plaja, Pere; Cots Reguant, Francesc; Mayer, Erick F.; Pérez Castejón, Joan Manuel; Vázquez, María Luisa (MDPI, 2021)

  Clinical coordination between primary (PC) and secondary care (SC) is a challenge for health systems, and clinical coordination mechanisms (CCM) play an important role in the interface between care levels. It is therefore ...
• Effectiveness of a psychoeducational group intervention carried out by nurses for patients with depression and physical comorbidity in primary care: randomized clinical trial

  Raya Tena, Antonia; Fernández-San-Martin, María Isabel; Martín Royo, Jaume; Casañas, Rocío; Sauch Valmaña, Glòria; Cols-Sagarra, Cèlia; Navas Mendez, Elena; Masa-Font, Roser; Casajuana-Closas, Marc; Foguet-Boreu, Quintí; Fernández Linares, Eva María; Mendioroz Peña, Jacobo; González Tejón, Susana; Martín López, Luis Miguel; Jiménez Herrera, María Francisca (MDPI, 2021)

  The association between physical illness and depression implies a poorer management of chronic disease and a lower response to antidepressant treatments. Our study evaluates the effectiveness of a psychoeducational group ...
• Consumption of ultra-processed food and drinks and chronic lymphocytic leukemia in the MCC-Spain study

  Solans, Marta; Fernández Barrés, Sílvia; Romaguera Bosch, Dora; Gracia Lavedan, Esther; Castaño Vinyals, Gemma; Kogevinas, Manolis; Casabonne, Delphine (MDPI, 2021)

  Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in Western countries. Its etiology is largely unknown but increasing incidence rates observed worldwide suggest that lifestyle and environmental ...
• Associations between greenspace and gentrification-related sociodemographic and housing cost changes in major metropolitan areas across the United States

  Schinasi, Leah H.; Cole, Helen; Hirsch, Jana A.; Hamra, Ghassan B.; Gullón, Pedro; Bayer, Felicia; Melly, Steven J.; Neckerman, Kathryn M.; Clougherty, Jane E.; Lovasi, Gina S. (MDPI, 2021)

  Neighborhood greenspace may attract new residents and lead to sociodemographic or housing cost changes. We estimated relationships between greenspace and gentrification-related changes in the 43 largest metropolitan ...
• A real-world study of the association between a brief group psychoeducation and the course of bipolar disorder

  Casellas, Elisabet; Raventós, Beatriz; Piñeiro Ríos, Marina; Navarro Martínez, Helena; Castillón Espezel, Maite; Portella, Maria J.; Martín Blanco, Ana (MDPI, 2021)

  Although pharmacotherapy is considered the first-line treatment for bipolar disorders (BD), adjunctive psychoeducation has proven its effectiveness in improving self-management of the disease and reducing relapse rates. ...
• Quantitative and qualitative evaluation of the COMPASS mobile app: a citizen science project

  Díaz, Jorge L.; Codern Bové, Núria; Zomeño Fajardo, Maria Dolores; Lassale, Camille; Schröder, Helmut, 1958-; Grau Magaña, Maria (Taylor & Francis, 2021)

  To evaluate the usability of the COMPASS application with mixed-methodology, using a citizen science approach. Parents/tutors of 10-11 years old children attending a primary school in Barcelona, Spain, were invited to take ...
• Environmental and individual exposure to secondhand aerosol of electronic cigarettes in confined spaces: Results from the TackSHS Project

  Amalia, Beladenta; Fu, Marcela; Tigova, Olena; Ballbé, Montse; Castellano, Yolanda; Semple, Sean; Clancy, Luke; Vardavas, Constantine; López, Maria José; Cortés, Nuria; Pérez Ortuño, Raúl, 1976-; Pascual, José A.; Fernández, Esteve (Wiley, 2021)

  Secondhand electronic cigarette (e-cigarette) aerosol (SHA) might impair indoor air quality and expose bystanders. This study aims to investigate exposure to SHA in controlled conditions of enclosed settings simulating ...

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