• Prediction of asthma hospitalizations for the common cold using google trends: infodemiology study

  Sousa Pinto, Bernardo; Halonen, Jaana I.; Antó, Aram; Jormanainen, Vesa; Czarlewski, Wienczyslawa; Bedbrook, Anna; Papadopoulos, Nikolaos; Freitas, Alberto; Haahtela, Tari; Antó i Boqué, Josep Maria; Almeida Fonseca, João; Bousquet, Jean (JMIR Publications, 2021)

  Background: In contrast to air pollution and pollen exposure, data on the occurrence of the common cold are difficult to incorporate in models predicting asthma hospitalizations. Objective: This study aims to assess whether ...
• Cannabidiol attenuates cognitive deficits and neuroinflammation induced by early alcohol exposure in a mice model

  García Baos, Alba; Puig Reyne, Xavier; García Algar, Oscar; Valverde Granados, Olga (Elsevier, 2021)

  Foetal alcohol spectrum disorder (FASD) is the umbrella term used to describe the physical and mental disabilities induced by alcohol exposure during development. Early alcohol exposure induces cognitive impairments resulting ...
• Functional assessment of coding and regulatory variants from the DKK1 locus

  Martínez-Gil, Núria; Roca Ayats, Neus; Atalay, Nurgül; Pineda-Moncusí, Marta; Garcia Giralt, Natàlia; Van Hul, Wim; Boudin, Eveline; Ovejero Crespo, Diana; Mellibovsky, Leonardo; Nogués Solan, Francesc Xavier; Diez Pérez, Adolfo; Grinberg, Daniel; Balcells, Susana (Wiley, 2020)

  The DKK1 gene encodes an extracellular inhibitor of the Wnt pathway with an important role in bone tissue development, bone homeostasis, and different critical aspects of bone biology. Several BMD genome-wide association ...
• Longitudinal associations of blood phosphorylated tau181 and neurofilament light chain with neurodegeneration in alzheimer disease

  Moscoso, Alexis; Grothe, Michel J.; Ashton, Nicholas J.; Karikari, Thomas K.; Lantero Rodriguez, Juan; Snellman, Anniina; Suárez-Calvet, Marc; Blennow, Kaj; Zetterberg, Henrik; Schöll, Michael; Alzheimer’s Disease Neuroimaging Initiative (American Medical Association, 2021)

  Importance: Plasma phosphorylated tau at threonine 181 (p-tau181) has been proposed as an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its ability to monitor disease progression ...
• Fiber burden and asbestos-related diseases: an umbrella review

  Ramada Rodilla, José María, 1961-; Calvo Cerrada, Beatriz; Serra, Consol; Delclos, George L.; Benavides, Fernando G. (Fernando García) (Elsevier, 2021)

  Objective: What are the levels of asbestos exposure that cause each type of health effect? The objective of this study was to review the available scientific evidence on exposure levels for asbestos and their relationship ...
• Repurposing benzbromarone for familial amyloid polyneuropathy: a new transthyretin tetramer stabilizer

  Cotrina, Ellen; Oliveira, Ângela; Leite, José Pedro; Llop, Jordi; Gales, Luis; Quintana, Jordi; Cardoso, Isabel; Arsequell, Gemma (MDPI, 2020)

  Transthyretin (TTR) is a homotetrameric protein involved in human amyloidosis, including familial amyloid polyneuropathy (FAP). Discovering small-molecule stabilizers of the TTR tetramer is a therapeutic strategy for these ...
• p53 immunohistochemical patterns in HPV-independent squamous cell carcinomas of the vulva and the associated skin lesions: a study of 779 cases

  Rakislova, Natalia; Alemany, Laia; Clavero, Omar; Saco, Adela; Torné, Aureli; Pino, Marta Del; Munmany, Meritxell; Rodrigo Calvo, Maria Teresa; Guerrero, José; Marimon, Lorena; Vega, Naiara; Quirós, Beatriz; Lloveras Rubio, Belen; Ribera-Cortada, Inmaculada; Alejo, María; Pawlita, Michael; Quint, Wim; Sanjosé Llongueras, Silvia de; Ordi, Jaume; Vvap Study Group (MDPI, 2020)

  Human papillomavirus (HPV)-independent vulvar squamous cell carcinomas (VSCC) and its precursors frequently harbour TP53 mutations. Recently, six p53 immunohistochemical (IHC) patterns have been defined, which have shown ...
• Nail melatonin content: a suitable non-invasive marker of melatonin production

  Gómez-Gómez, Àlex; Montero-San-Martin, Blanca; Haro, Noemí; Pozo Mendoza, Óscar J. (MDPI, 2021)

  Melatonin plays multiple physiological roles in the human body. Evaluation of melatonin production by the determination of urinary 6-sulfatoxymelatonin in 24-h samples has important drawbacks which hinder the successful ...
• Schuurs-Hoeijmakers syndrome (PACS1 neurodevelopmental disorder): seven novel patients and a review

  Tenorio Castaño, Jair; Pérez Jurado, Luis Alberto; Lapunzina, Pablo Daniel (MDPI, 2021)

  Schuurs-Hoeijmakers syndrome (SHMS) or PACS1 Neurodevelopmental disorder is a rare disorder characterized by intellectual disability, abnormal craniofacial features and congenital malformations. SHMS is an autosomal dominant ...
• Genetic predisposition to Alzheimer's disease is associated with enlargement of perivascular spaces in centrum semiovale region

  Ciampa, Iacopo; Operto, Grégory; Falcón, Carles; Minguillón, Carolina; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Molinuevo, José Luis; Guigó Serra, Roderic; Navarro i Cuartiellas, Arcadi, 1969-; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; ALFA Study (MDPI, 2021)

  This study investigated whether genetic factors involved in Alzheimer's disease (AD) are associated with enlargement of Perivascular Spaces (ePVS) in the brain. A total of 680 participants with T2-weighted MRI scans and ...
• Gynecologic cancer surveillance in the era of SARS-CoV-2 (COVID-19)

  Mancebo Moreno, Gemma; Solé-Sedeño, Josep Maria; Membrive, Ismael; Taus García, Álvaro; Castells Zaragoza, Marta; Serrano, Laia; Carreras Collado, Ramón; Miralpeix, E. (BMJ Publishing Group, 2021)

  The SARS-CoV-2 (COVID-19) pandemic has significantly impacted the management of patients with gynecologic cancers. Many centers have reduced access to routine visits to avoid crowded waiting areas and specially to reduce ...
• Validation of an asbestos exposure questionnaire (QEAS-7) for clinical practice

  Ferrer, Jaume; Granados, Galo; Hernández, Santos; Cruz, María-Jesús; Sampol, Júlia; Álvarez Simón, Daniel; Ramada Rodilla, José María, 1961- (MDPI, 2020)

  Introduction: The seven-item QEAS-7 questionnaire (exposure to asbestos questionnaire) has been designed as a useful and simple tool to establish the probability of exposure to asbestos. The objective of the present study ...
• Epidemiology and costs of depressive disorder in Spain: the EPICO study

  Vieta, Eduard; Alonso Caballero, Jordi; Pérez Solá, Victor; Roca, Miquel; Hernando, Teresa; Sicras Navarro, Aram; Herrera, Berta; Gabilondo Cuéllar, Andrea (Elsevier, 2021)

  Depressive Disorders are the most common psychiatric diagnoses in the general population. To estimate the frequency, costs associated with Depressive Disorders in usual clinical practice, and in the whole Spanish population, ...
• Subgrouping a large U.S. sample of patients with fibromyalgia using the fibromyalgia impact questionnaire-revised

  Pérez-Aranda, Adrián; Feliu-Soler, Albert; Mist, Scott D.; Jones, Kim D.; López-Del-Hoyo, Yolanda; Oliván-Arévalo, Rebeca; Kratz, Anna; Williams, David A.; Luciano, Juan V. (MDPI, 2020)

  Fibromyalgia (FM) is a heterogeneous and complex syndrome; different studies have tried to describe subgroups of FM patients, and a 4-cluster classification based on the Fibromyalgia Impact Questionnaire-Revised (FIQR) has ...
• Residential surrounding greenspace and mental health in three spanish areas

  Torres Toda, Maria; Anabitarte Riol, Asier; Cirach, Marta; Estarlich, Marisa; Fernández-Somoano, Ana; González-Safont, Llúcia; Guxens Junyent, Mònica; Julvez, Jordi; Riaño, Isolina; Sunyer Deu, Jordi; Dadvand, Payam (MDPI, 2020)

  Exposure to greenspace has been related to improved mental health, but the available evidence is limited and findings are heterogeneous across different areas. We aimed to evaluate the associations between residential ...
• Quality of life in a cohort of 1078 women diagnosed with breast cancer in spain: 7-year follow-up results in the MCC-Spain Study

  Alonso Molero, Jessica; Castaño Vinyals, Gemma; Castells, Xavier; Kogevinas, Manolis; Llorca, Javier (MDPI, 2020)

  Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this ...
• Maternal ferritin levels during pregnancy and ADHD symptoms in 4-year-old children: results from the INMA-INfancia y Medio Ambiente (environment and childhood) prospective birth cohort study

  Santa Marina, Loreto; Lertxundi, Nerea; Andiarena, Ainara; Irizar, Amaia; Sunyer Deu, Jordi; Molinuevo, Amaia; Llop, Sabrina; Júlvez Calvo, Jordi; Beneito, Andrea; Ibarluzea, Jesús; Imaz, Liher; Ferrin, Maite (MDPI, 2020)

  Ferritin status during prenatal brain development may influence the risk of attention deficit and hyperactivity disorder (ADHD) symptoms in childhood. We investigated the association of maternal ferritin in pregnancy and ...
• Framework for participatory quantitative health impact assessment in low- and middle-income countries

  Thondoo, Meelan; de Vries, Daniel H.; Rojas Rueda, David, 1979-; Ramkalam, Yashila D.; Verlinghieri, Ersilia; Gupta, Joyeeta; Nieuwenhuijsen, Mark J. (MDPI, 2020)

  Background: Conducting health impact assessments (HIAs) is a growing practice in various organizations and countries, yet scholarly interest in HIAs has primarily focused on the synergies between exposure and health outcomes. ...
• Dietary constituents: relationship with breast cancer prognostic (MCC-SPAIN Follow-Up)

  Dierssen Sotos, Trinidad; Castaño Vinyals, Gemma; Kogevinas, Manolis; Llorca, Javier (MDPI, 2020)

  The aim of this study was to characterize the relationship between the intake of the major nutrients and prognosis in breast cancer. A cohort based on 1350 women with invasive (stage I-IV) breast cancer (BC) was followed ...
• Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC-Spain study)

  Weitzer, Jakob; Castaño Vinyals, Gemma; Kogevinas, Manolis (Wiley, 2021)

  Experimental evidence indicates that exercise performed at different times of the day may affect circadian rhythms and circadian disruption has been linked to breast and prostate cancer. We examined in a population-based ...

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