• Exploratory analyses of treatment subgroup interaction by PD-L1 status and according to PD-L1 expression in the JAVELIN Bladder 100 trial

  Rodriguez-Vida, Alejo (Springer, 2024)
• Tubulo-interstitial inflammation increases the risk of graft loss after the recurrence of IgA nephropathy

  Buxeda, Anna (Oxford University Press, 2023)
• Factors associated with disease progression in patients with atrial fibrillation and heart failure anticoagulated with rivaroxaban

  Farré López, Núria (Wiley, 2024)
• Comparative effectiveness of new treatment modalities for localized prostate cancer through patient-reported outcome measures

  Ferrer Forés, Montserrat (Elsevier, 2023)
• A global perspective on stepping down chronic spontaneous urticaria treatment: Results of the Urticaria Centers of Reference and Excellence SDown-CSU study

  Giménez Arnau, Anna Maria (Wiley, 2024)
• Update on the management of older patients with pancreatic adenocarcinoma: a perspective from medical oncology

  Visa Turmo, Laura (Springer, 2024)
• Minimal important difference of the 12-item World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in persons with chronic low back pain

  Ferrer Forés, Montserrat (BioMed Central, 2023)
• NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy

  Hurtado Navarro, Laura; Bellosillo Paricio, Beatriz; García Ávila, Sara; Ferrer-Marín, Francisca (Elsevier, 2023)

  Chronic myelomonocytic leukemia (CMML) is frequently associated with mutations in the rat sarcoma gene (RAS), leading to worse prognosis. RAS mutations result in active RAS-GTP proteins, favoring myeloid cell proliferation ...
• Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis

  Medina Dols, Aina; Mola Caminal, Marina; Soriano Tarraga, Carolina; Giralt-Steinhauer, Eva; Lazcano Dobao, Uxue; Fernández-Pérez, Isabel; Jiménez-Balado, Joan; Jiménez Conde, Jordi; Vives Bauzá, Cristòfol (Nature Research, 2024)

  Through GWAS studies we identified PATJ associated with functional outcome after ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial cells (ECs) in the context of stroke outcome. ...
• Plasma metabolite profile of legume consumption and future risk of type 2 diabetes and cardiovascular disease

  Margara Escudero, Hernando J.; Castañer, Olga; Salas Salvadó, Jordi (BioMed Central, 2024)

  Background: Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and ...
• Trend and joinpoint analysis of cancer incidence and 1-Year mortality in north-east Spain 2005-2020

  Roura-Poch, Pere; Puigoriol, Emma; Altimiras, Jacint; Batiste Alentorn, Eduard; Dégano, Irene R. (MDPI, 2023)

  Cancer is the second leading cause of death. It is thus essential to examine cancer trends in all regions. In addition, trend data after 2019 and on cancer 1-year mortality are scarce. Our aim was to analyze incidence and ...
• The C250T mutation of TERTp might grant a better prognosis to glioblastoma by exerting less biological effect on telomeres and chromosomes than the C228T mutation

  Gorria, Teresa; Crous-Bou, Marta; Pineda, Estela; Hernandez, Ainhoa; Domenech, Marta; Sanz, Carolina; Jares, Pedro; Muñoz Mármol, Ana María; Arpí Llucià, Oriol; Meléndez, Bárbara; Gut, Marta; Esteve, Anna; Esteve-Codina, Anna; Parra Farré, Genís; Alameda Quitllet, Francisco; Carrato, Cristina; Aldecoa, Iban; Mallo, Mar; Iglesia, Nuria de la; Balana, Carmen (MDPI, 2024)

  The aim of this study was to determine how TERTp mutations impact glioblastoma prognosis. Materials and methods: TERTp mutations were assessed in a retrospective cohort of 258 uniformly treated glioblastoma patients. ...
• Cell-Free DNA as a biomarker at diagnosis and follow-up in 256 B and T-Cell lymphomas

  Díez-Feijóo, Ramón; Andrade-Campos, Marcio; Gibert Fernandez, Joan, 1988-; Sánchez González, Blanca; Fernández-Ibarrondo, Lierni; Fernández Rodríguez, M. Concepción; García Gisbert, Nieves, 1994-; Camacho Díaz, Laura; Lafuente, Marta; Vázquez, Ivonne; Colomo Saperas, Luis Alberto; Salar Silvestre, Antonio; Bellosillo Paricio, Beatriz (MDPI, 2024)

  Background: Cell-free DNA (cfDNA) analysis has become a promising tool for the diagnosis, prognosis, and monitoring of lymphoma cases. Until now, research in this area has mainly focused on aggressive lymphomas, with scanty ...
• Apalutamide for prostate cancer: Multicentre and multidisciplinary real-world study of 227 patients

  Córdoba Sánchez, Julián; Picola, Natàlia; Rodriguez-Vida, Alejo; Costa, Marc; Marmolejo Castañeda, David; Pérez Márquez, Meritxell; Muñoz Rodriguez, Jesús; Gaya Sopena, Josep Maria; Bravo, Alejandra; Buisan, Oscar; Servian, Pol; Suárez Novo, José Francisco; Musquera Felip, Mireia; Ribal Caparrós, Maria Jose; Alcaraz Asensio, Antonio; Vilaseca, Antoni (Wiley, 2023)

  Objective: To evaluate the efficacy and safety of apalutamide prostate cancer compared to the pivotal trials patients and to identify the first subsequent therapy in a real-world setting. Methods: The study is prospective ...
• Benralizumab does not elicit therapeutic effect in patients with chronic spontaneous urticaria: results from the phase IIb multinational randomized double-blind placebo-controlled ARROYO trial

  Altrichter, Sabine; Giménez Arnau, Anna Maria; Bernstein, Jonathan A.; Metz, Martin; Bahadori, Lila; Bergquist, Maria; Brooks, Laura; Ho, Calvin N.; Jain, Priya; Lukka, Pradeep B.; Rodriguez-Suárez, Eva; Walton, Claire; Datto, Catherine J.; ARROYO Study Investigators (Oxford University Press, 2024)

  Background: Chronic spontaneous urticaria (CSU) is a relatively common skin disease associated with hives and angio-oedema. Eosinophils play a role in CSU pathogenesis. Benralizumab, an anti-interleukin-5 receptor-α ...
• APOE ɛ4 exacerbates age-dependent deficits in cortical microstructure

  Mak, Elijah; Falcón, Carles; Gispert López, Juan Domingo; PREVENT-Dementia and ALFA studies (Oxford University Press, 2024)

  The apolipoprotein E ɛ4 allele is the primary genetic risk factor for the sporadic type of Alzheimer's disease. However, the mechanisms by which apolipoprotein E ɛ4 are associated with neurodegeneration are still poorly ...
• Neurosurgical training and education - General European certification is supported: Results of an EANS survey

  Navarro Canals, Ramon; Mehigan, Benjamin; Marchesini, Nicolò; Demetriades, Andreas K.; Lafuente Baraza, Jesus (Elsevier, 2023)

  Introduction: Delivering high-quality Neurosurgical care is dependent on excellence in neurosurgical training. Across Europe requirements of these programs vary from state to state. This study aims to determine satisfaction ...
• Management of incidental durotomies in an integrated Orthopaedic and Neurosurgical Spinal Unit

  Rodríguez Rubio, David; Amin, U.; Bartolomé, D.; Pont Acuña, Àngels; Arco Churruca, Alejandro del; Saló Bru, Guillem; Vilá, G.; Isart Torruella, Anna; Manzano Espinosa, Dulce; Lafuente Baraza, Jesus (Elsevier, 2023)

  Introduction: Incidental durotomy (ID) is an intraoperative event associated to prolonged bed rest and hospital stay, antibiotic use, higher patient dissatisfaction, and leg pain among other complications of its postoperative ...
• Clinicopathological correlates in the frontotemporal lobar degeneration-motor neuron disease spectrum

  Carbayo, Álvaro; Rubio Pérez, Miguel Angel; Rojas-García, Ricard (Oxford University Press, 2024)

  Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease (MND) that shares a common clinical, genetic and pathologic spectrum with frontotemporal dementia (FTD). It is highly heterogeneous in its presentation ...
• The practicality of using bone impact microindentation in a population-based study of women: A Geelong-Osteoporosis Study

  Rufus-Membere, Pamela; Anderson, Kara B.; Holloway-Kew, Kara L.; Harland, Jacob W.; Diez-Perez, Adolfo; Kotowicz, Mark A.; Pasco, Julie A. (Elsevier, 2024)

  Impact microindentation (IMI) is a minimally invasive technique that allows the assessment of bone material strength index (BMSi) in vivo, by measuring the depth of a micron-sized, spherical tip into cortical bone that is ...

View more