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SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements

Mostra el registre parcial de l'element Castellano Hereza, Sergi Gladyshev, Vadim N. Guigó Serra, Roderic Berry, Marla J.
dc.contributor.other Universitat Pompeu Fabra 2011-11-28T11:08:03Z 2011-11-28T11:08:03Z 2008
dc.identifier.citation Castellano S, Gladyshev V N, Guigó R, Berry M J. SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements. Nucleic acids research. 2008; 36 supl 1: D332-D338. DOI 10.1093/nar/gkm731
dc.identifier.issn 0305-1048
dc.description.abstract Selenoproteins are a diverse group of proteins/nusually misidentified and misannotated in sequence/ndatabases. The presence of an in-frame UGA (stop)/ncodon in the coding sequence of selenoprotein/ngenes precludes their identification and correct/nannotation. The in-frame UGA codons are recoded/nto cotranslationally incorporate selenocysteine,/na rare selenium-containing amino acid. The development/nof ad hoc experimental and, more recently,/ncomputational approaches have allowed the efficient/nidentification and characterization of the/nselenoproteomes of a growing number of species./nToday, dozens of selenoprotein families have been/ndescribed and more are being discovered in recently/nsequenced species, but the correct genomic annotation/nis not available for the majority of these/ngenes. SelenoDB is a long-term project that aims to/nprovide, through the collaborative effort of experimental/nand computational researchers, automatic/nand manually curated annotations of selenoprotein/ngenes, proteins and SECIS elements. Version 1.0 of/nthe database includes an initial set of eukaryotic/ngenomic annotations, with special emphasis on the/nhuman selenoproteome, for immediate inspection/nby selenium researchers or incorporation into more/ngeneral databases. SelenoDB is freely available at/n
dc.language.iso eng
dc.publisher Oxford University Press
dc.rights (c) 2007 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Published article is also available at
dc.subject.other Biologia molecular
dc.subject.other Bioinformàtica
dc.subject.other Genòmica -- Bases de dades
dc.subject.other Genòmica -- Informàtica
dc.title SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements
dc.type info:eu-repo/semantics/article
dc.subject.keyword 3'UTR
dc.subject.keyword Protein databases
dc.subject.keyword Genomics
dc.subject.keyword Humans
dc.subject.keyword Internet
dc.subject.keyword Selenoproteins
dc.subject.keyword Protein Sequence Analysis
dc.subject.keyword RNA Sequence Analysis
dc.subject.keyword User-Computer Interface
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.type.version info:eu-repo/semantics/publishedVersion

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