A functional study of the conserved LSM proteins in C. elegans reveals their involvement in the stress response of metazoans [datasets]

Cornes Maragliano, Eric, 1987-

A functional study of the conserved LSM proteins in C. elegans reveals their involvement in the stress response of metazoans [datasets]

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Cornes Maragliano, E. A functional study of the conserved LSM proteins in C. elegans reveals their involvement in the stress response of metazoans [datasets]. 2015. handle: http://hdl.handle.net/10230/25608

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Abstract

Research data from the thesis “A functional study of the conserved LSM proteins in C. elegans reveals their involvement in the stress response of metazoans” by Eric Cornes http://hdl.handle.net/10803/315473

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Table S1. RNAi phenotypes of lsm genes retrieved from wormmart./nWormmart is a tool available at wormbase [S1]. RNAi assays represented in this table were performed following diverse protocols and using distinct genetic backgrounds: /nRNAi by feeding starting at L4 [S2], RNAi by feeding starting at L1 [S3], RNAi in RNAi hypersensitive backgrounds [S4, S5], RNAi by injection [S6], or RNAi by soaking [S7]. Other RNAi screens referred here were focused in specific phenotypes as aging, cell proliferation, endocytosis, innate immunity or transgene silencing [S8–13]./n/nTable S2. Yeast lsm phenome./nTable shows all the yeast lsm phenotypes retrieved from the Saccharomyces Genome Database (SGD) [S13]. All the information available for S. cerevisiae mutant strains for lsm genes is shown. Non-viable phenotypes are highlighted in red. /n/nTable S3. RNA-Seq analyses of lsm-1 mutants. /nSheet 1: Statistical analyses including FPKM (fragments per kilobase of exon per million fragments mapped) for each gene mapped, and fold change between lsm-1 mutants and wild type animals. /nSheet 2: Genes significantly upregulated (p value ≤ 0.05). /nSheet 3: Genes significantly downregulated (p value ≤ 0.05). /nSheets 4 and 5: Additional information about genes up and down regulated in lsm-1 mutants. Gene description was retrieved from wormbase using the tool wormmart.