• Global prevalence and incidence of Alzheimer’s disease and mild cognitive impairment

  Díaz Guindo, Marta (2021)

  Alzheimer’s disease (AD) is the most prevalent cause of dementia worldwide. AD is characterized histopathologically by senile plaques composed of amyloid β-peptide (Aβ) and neurofibrillary tangles consisting of aggregated ...
• Elucidating the pathophysiological role of the apoptosis inducing factor 1 (AIF1) in Alzheimer's disease: a review of its participation in other pathologies

  Solé Ariza, Aina (2021)

  Alzheimer’s disease (AD) is the most common cause of age-related dementia, whose progression and development are explained by two well-based hypotheses. The amyloid cascade hypothesis proposes the aggregation of the amyloid ...
• Study of the molecular basis of congenital disorders of glycosylation using yeast as a model organism

  Guiu Gonzalez, Neus (2021)

  Congenital Disorders of Glycosylation (CDG) are a group of inherited human disorders caused by defects on protein glycosylation. Rft1-CDG is a form of CDG caused by mutations in the gene RFT1. Rft1 is a conserved protein ...
• Inhibition of TELO2 sensitizes colorectal cancer cells to chemotherapies

  Ortiz Gràcia, Alba (2019)

  Colorectal cancer is the 2nd most killing cancer around the world. Because treatments generally involve DNA damage, high toxicity and undesirable effects are frequently observed, which lead to treatment suspension. Moreover, ...
• The role of the neuroimmune system in the pathogenesis of fetal alcohol spectrum disorders

  Sopena Rios, Maria (2020)

  Fetal alcohol spectrum disorders (FASD) results from maternal consumption of alcohol during pregnancy. Yet preventable, it still is very prevalent as it is estimated that 50% of the women of childbearing age consume alcohol ...
• Antimicrobial stewardship strategies against extended-spectrum β-lactamase-carrying enterobacterales: a review

  Rovira i Plujà, Jana (2021)

  Multidrug-resistant and extremely-drug resistant (MDR/XDR) Gram-negative bacteria (GNB) are responsible of most healthcare-associated infections worldwide. Antimicrobial stewardship (AMS) and infection control strategies ...
• EcR depletion affects ovarian follicle differentiation and oocyte growth in the cockroach Blattella germanica

  Rumbo Roig, Mireia (2020)

  Ecdysteroid hormones in insects regulate a diverse amount of physiological processes during developmental and adult stages. The molecular basis of ecdysteroid signalling has been deeply studied in holometabolous insects ...
• The role of Nuclear factor I A (Nfia) during late embryonic neurogenesis

  Río Bergé, Clàudia (2021)

  The Nuclear factor I A (Nfia) is a transcription factor which seems to be a key element during late embryonic brain neurogenesis. Since most of the studies about the role of Nfia in the Central Nervous System (CNS) are ...
• Antropología de la Guerra Civil Española en Cataluña: estudio de la exhumación de fosas e identificación de víctimas desde 1999 a 2020

  Sevillano Oriola, Laia (2020)

  La Guerra Civil Española (1936-1939) y el principio de la dictadura franquista dejaron muchas víctimas fruto de la violencia y represión, muchas de las cuales fueron enterradas en fosas comunes. Concretamente en Cataluña, ...
• Towards a more sustainable university: exploring PBL-SDG innovative strategies to contribute to the sustainable development

  Llerena Bastida, Maria (2020)

  With a view to the Sustainable Development Goals (SDG), UNESCO has been promoting the Education for Sustainable Development (ESD) as a transformational tool to educate critically literate, socially connected and ethically ...
• Implementation of targeted proteomics methods for the characterization of peptides and proteins in liquid biopsies

  Vila Escutia, Laia (2020)

  Targeted proteomics methods emerged to detect and quantify well-defined sets of peptides with a high degree of specificity and sensitivity. Internal standard triggered-PRM (IS-PRM) was designed to increase the number of ...
• Effects of variability in second language learning in adults

  Sánchez López, Rebeca (2020)

  Learning a second language is a difficult task for adults. The present thesis explored how variability in the number of teachers influences second language learning and how this process is modulated by the similarity of ...
• Revisió i actualització de les entrades de fàrmacs indispensables en el nou Diccionari enciclopèdic de medicina (DEMCAT)

  Cerrillo Moya, Carlota; Escala Crusells, Clara (2020)

  D’ençà que es va publicar el Diccionari de medicina de Manuel Corachan, l’any 1936, la terminologia mèdica en català no ha evolucionat a un ritme constant; ans al contrari, ha hagut de superar nombrosos entrebancs. Gairebé ...
• Pavel Florensky, reverse perspective and the neurosciences

  Díaz Calvete, Júlia (2019)

  The way we perceive the world has always been a major concern of philosophy and art. Pavel Florensky was a Russian polymath who wrote Reverse Perspective (1920), a rather unique essay on perception and art. His analysis ...
• Spontaneous neuronal activity is correlated to statistical learning performance: computation of ALFF and fALFF indices on resting-state fMRI

  Sanahuja Irene, Sandra (2019)

  Statistical learning (SL) is a mechanism that enables us to detect and learn probabilistic regularities and patterns from the environment. Previous studies have explored the role of SL in resting-state functional connectivity, ...
• Dispositiu mèdic per combatre la falta de sacietat en pacients amb Síndrome de Prader-Willi

  Figueras Cervera, Marta; Garcia Codina, Gal·la (2019-08-01)

  La Síndrome de Prader-Willi (SPW) és un trastorn poc freqüent causat per una falta d’expressió del cromosoma 15. Els afectats pateixen afectacions mentals, físiques i conductuals. Els resultats d’una enquesta realitzada ...
• Targeting acute myeloid leukemia stem cell: current status and clinical application

  Gutierrez Tordera, Laia (2019-08-01)

  Since the discovery of leukemic stem cells by Dick and Bonnet in 1996, therapeutic targets have been searched to specifically eliminate this population and, thus, avoid recurrent episodes of relapse in these patients. To ...
• Analysis of the cholinergic system in Alzheimer’s disease: a study of toxicity and regulation of stress response in cholinergic cells

  Salvador i Mata, Bertran (2015-06-19)

  Alzheimer’s disease, the most common cause of dementia, is a chronic neurodegenerative disorder that slowly impairs the cognitive abilities of the patient, leading to a progressive neuronal loss. The main molecular ...
• Identification of war victims of the 20th century from Poland through DNA testing from skeletal remains

  Badell Garcia, Irina (2018-09-13)

  Identification through forensic methods is crucial in crime investigations. The Polish Genetic Database of Victims of Totalitarianism (PBGOT) is allowing the positive identification of many victims of Communist and Nazi ...
• Nanoheaters and amoeboid-like motile cells: designing a new delivery system

  Bellot Herrero, Carlota (2018-09-13)

  Pharmacological success is strongly determined by how a drug is delivered to its target structure. This is the reason why the development of improved and new drug delivery strategies is one of the greatest pharmacological ...

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