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Examinant per Autoria "Lehner, Ben, 1978-"

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    A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression

    (Elsevier, 2016) Bolognesi, Benedetta; Lorenzo Gotor, Maria de las Nieves; Dhar, Riddhiman; Cirillo, Davide; Baldrighi, Marta; Gaetano Tartaglia, Gian; Lehner, Ben, 1978-

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    An atlas of amyloid aggregation: the impact of substitutions, insertions, deletions and truncations on amyloid beta fibril nucleation

    (Nature Research, 2022) Seuma, Mireia; Lehner, Ben, 1978-; Bolognesi, Benedetta

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    ÍtemAccés Obert
    An extension of the Walsh-Hadamard transform to calculate and model epistasis in genetic landscapes of arbitrary shape and complexity

    (Public Library of Science (PLoS), 2024) Faure, Andre J.; Lehner, Ben, 1978-; Miró Pina, Verónica; Serrano Colomé, Clàudia; Weghorn, Donate

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    Miniatura
    ÍtemAccés Obert
    Biophysical ambiguities prevent accurate genetic prediction

    (Nature Research, 2020) Li, Xianghua; Lehner, Ben, 1978-

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    Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types

    (Wiley Blackwell, 2015) Park, Solip; Lehner, Ben, 1978-

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    ÍtemAccés Obert
    Changes in gene expression predictably shift and switch genetic interactions

    (Nature Research, 2019) Li, Xianghua; Lalić, Jasna; Baeza Centurión, Pablo, 1989-; Dhar, Riddhiman; Lehner, Ben, 1978-

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    Clustered mutation signatures reveal that error-prone DNA repair targets mutations to active genes

    (Elsevier, 2017) Supek, Fran; Lehner, Ben, 1978-

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    Miniatura
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    Co-option of the piRNA pathway for germline-specific alternative splicing of C. elegans TOR

    (Cell Press, 2014) Barberán-Soler, Sergio; Fontrodona, Laura; Ribó Rubio, Anna; Lamm, Ayelet T.; Iannone, Camilla, 1984-; Cerón, Julián; Lehner, Ben, 1978-; Valcárcel, J. (Juan)

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    Conserved substitution patterns around nucleosome footprints in eukaryotes and archaea derive from frequent nucleosome repositioning through evolution

    (Public Library of Science (PLoS), 2013) Warnecke, Tobias ; Becker, Erin A.; Facciotti, Marc T.; Nislow, Corey; Lehner, Ben, 1978-

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    Deep indel mutagenesis reveals the impact of amino acid insertions and deletions on protein stability and function

    (Nature Research, 2025) Topolska, Magdalena; Beltran, Antoni; Lehner, Ben, 1978-

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    ÍtemAccés Obert
    Determining protein structures using deep mutagenesis

    (Nature Research, 2019) Schmiedel, Jörn M.; Lehner, Ben, 1978-

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    Differential DNA mismatch repair underlies mutation rate variation across the human genome

    (Nature Publishing Group, 2015) Supek, Fran; Lehner, Ben, 1978-

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    Miniatura
    ÍtemAccés Obert
    DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies

    (BioMed Central, 2020) Faure, Andre J.; Schmiedel, Jörn M.; Baeza Centurión, Pablo, 1989-; Lehner, Ben, 1978-

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    Dissecting the calcium-induced differentiation of human primary keratinocytes stem cells by integrative and structural network analyses

    (Public Library of Science (PLoS), 2015) Toufighi, Kiana, 1980-; Yang, Jae-Seong; Luis, Nuno Miguel, 1982-; Aznar Benitah, Salvador; Lehner, Ben, 1978-; Serrano Pubull, Luis, 1982-; Kiel, Christina

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    Dominance vs epistasis: the biophysical origins and plasticity of genetic interactions within and between alleles

    (Nature Research, 2023) Xie, Xuan; Sun, Xia; Wang, Yuheng; Lehner, Ben, 1978-; Li, Xianghua

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    Miniatura
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    Empirical mean-noise fitness landscapes reveal the fitness impact of gene expression noise

    (Nature Research, 2019) Schmiedel, Jörn M.; Carey, Lucas, 1980-; Lehner, Ben, 1978-

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    ÍtemAccés Obert
    Epigenetic epistatic interactions constrain the evolution of gene expression

    (EMBO Press, 2013) Park, Solip; Lehner, Ben, 1978-

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    Harmonious genetic combinations rewire regulatory networks and flip gene essentiality

    (Nature Research, 2019) New, Aaron M.; Lehner, Ben, 1978-

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    Higher order genetic interactions switch cancer genes from two-hit to one-hit drivers

    (Nature Research, 2021) Park, Solip; Supek, Fran; Lehner, Ben, 1978-

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    Human epidermal stem cell function is regulated by circadian oscillations

    (Elsevier, 2013) Janich, Peggy, 1981-; Toufighi, Kiana, 1980-; Solanas, Guiomar; Luis, Nuno Miguel, 1982-; Minkwitz, Susann; Serrano Pubull, Luis, 1982-; Lehner, Ben, 1978-; Aznar Benitah, Salvador

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