Montero, Maria MilagroMir Fontana, M. LuisaSulleiro, ElenaAvalos Esquivel, J.L.García López, E.Molina-Morant, D.López Montesinos, InmaculadaSorli Redó, M. LuisaVeliz Espinosa, G.Mounteis Oliva, E.Crespo Barrio, MartaMonge, I.Horcajada Gallego, Juan PabloGrau Cerrato, SantiagoPascual Santos, Julio2019-05-282019-05-282019Montero M, Mir M, Sulleiro E, Avalos Esquivel JL, García López E, Molina-Morant D et al. High-dose benznidazole in a 62-year-old Bolivian kidney transplant recipient with Chagas central nervous system involvement. Int J Infect Dis. 2019 Jan;78:103-6. DOI: 10.1016/j.ijid.2018.10.0141201-9712http://hdl.handle.net/10230/41635There is little published data on benznidazole dosing, or levels in cerebrospinal fluid. In this report, we describe the clinical course of an immunosuppressed patient with Chagas central nervous system involvement. He was treated successfully with larger benznidazole doses than are recommended, in order to reach therapeutically effective concentrations in the brain.application/pdfeng1201-9712/© 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.This is an open access article under the CCBY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Chagas, Malaltia deRonyons -- Trasplantacióinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.ijid.2018.10.014Benznidazole PK/PDBenznidazole doseChagas diseaseChagomaKidney transplant recipientinfo:eu-repo/semantics/openAccess