Dyke, Stephanie O. M.Connor, KathleenNembaware, VictoriaMunung, Nchangwi S.Reinold, KathyKerry, GiselleMbiyavanga, MamanaZass, LyndonMoldes, MauricioDas, SamirDavis, John M.Rambla de Argila, JordiSpalding, J. DylanEvans, Alan C.Mulder, NicolaKaramchandani, Jason2023-02-242023-02-242023Dyke SOM, Connor K, Nembaware V, Munung NS, Reinold K, Kerry G, Mbiyavanga M, Zass L, Moldes M, Das S, Davis JM, De Argila JR, Spalding JD, Evans AC, Mulder N, Karamchandani J. Consent codes: Maintaining consent in an ever-expanding open science ecosystem. Neuroinformatics. 2023 Jan;21(1):89-100. DOI: 10.1007/s12021-022-09577-41539-2791http://hdl.handle.net/10230/55904We previously proposed a structure for recording consent-based data use 'categories' and 'requirements' - Consent Codes - with a view to supporting maximum use and integration of genomic research datasets, and reducing uncertainty about permissible re-use of shared data. Here we discuss clarifications and subsequent updates to the Consent Codes (v4) based on new areas of application (e.g., the neurosciences, biobanking, H3Africa), policy developments (e.g., return of research results), and further practical considerations, including developments in automated approaches to consent management.application/pdfeng© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Consent codes: Maintaining consent in an ever-expanding open science ecosysteminfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s12021-022-09577-4ConsentData accessData managementData sharingEthicsOpen scienceinfo:eu-repo/semantics/openAccess