Pognan, FrançoisCenteno, EmilioFurlong, Laura I., 1971-Guney, EmreMayer, Miguel Ángel, 1960-Pastor Maeso, ManuelPiñero González, Janet, 1977-Ramírez Anguita, Juan ManuelRonzano, FrancescoSaüch Pitarch, JosepSanz, Ferran2021-04-122021-04-122021Pognan F, Steger-Hartmann T, Díaz C, Blomberg N, Bringezu F, Briggs K et al. The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives. Pharmaceuticals (Basel). 2021; 14(3):237. DOI: 10.3390/ph140302371424-8247http://hdl.handle.net/10230/47087eTRANSAFE is a research project funded within the Innovative Medicines Initiative (IMI), which aims at developing integrated databases and computational tools (the eTRANSAFE ToxHub) that support the translational safety assessment of new drugs by using legacy data provided by the pharmaceutical companies that participate in the project. The project objectives include the development of databases containing preclinical and clinical data, computational systems for translational analysis including tools for data query, analysis and visualization, as well as computational models to explain and predict drug safety events.application/pdfeng© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/ph14030237Data miningData sharingDrug safetyIntegrative knowledge managementPredictive modellingRead acrossToxicologyTranslational safety assessmentinfo:eu-repo/semantics/openAccess