Baulida i Estadella, Josep, 1965-Díaz Cortés, Víctor Manuel, 1956-García de Herreros, Antonio2020-02-072020-02-072019Baulida J, Díaz VM, Herreros AG. Snail1: A Transcriptional Factor Controlled at Multiple Levels. J Clin Med. 2019 May 28;8(6):757. DOI: 10.3390/jcm80607572077-0383http://hdl.handle.net/10230/43518Snail1 transcriptional factor plays a key role in the control of epithelial to mesenchymal transition and fibroblast activation. As a consequence, Snail1 expression and function is regulated at multiple levels from gene transcription to protein modifications, affecting its interaction with specific cofactors. In this review, we describe the different elements that control Snail1 expression and its activity both as transcriptional repressor or activator.application/pdfengCopyright © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)info:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/jcm8060757Epithelial to mesenchymal transition (EMT)Snail1Drug resistanceTranscriptional factorTumor invasioninfo:eu-repo/semantics/openAccess