Solana, RafaelTarazona, RaquelAiello, Allison E.Akbar, Arne N.Appay, VictorBeswick, MarkBosch, Jos A.Campos, CarmenCantisán, SaraCicin Sain, LucaDerhovanessian, EvelynaFerrando Martínez, SaraFrasca, DanielaFulöp, TamasGovind, SheilaGrubeck Loebenstein, BeatrixHill, AnnHurme, MikkoKern, FlorianLarbi, AnisLópez-Botet, M. (Miguel)Maier, Andrea B.McElhaney, Janet E.Moss, PaulNaumova, ElissavetaNikolich Zugich, JankoPera, AlejandraRector, Jerrarld L.Riddell, NatalieSanchez Correa, BeatrizSansoni, PaoloSauce, DelphineLier, Rene vanWang, George C.Wills, Mark R.Zielinski, MaciejPawelec, Graham2015-03-162015-03-162012Solana R, Tarazona R, Aiello AE, Akbar AN, Appay V, Beswick M et al. CMV and Immunosenescence: from basics to clinics. Immunity & Ageing. 2012; 9: 23. DOI 10.1186/1742-4933-9-231742-4933http://hdl.handle.net/10230/23187Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers and proportions of peripheral immune cells in infected-vs-uninfected people. Because the rate of CMV infection increases with age in most countries, it has been suggested that it drives or at least exacerbates “immunosenescence”. This contention remains controversial and was the primary subject of the Third International Workshop on CMV & Immunosenescence which was held in Cordoba, Spain, 15-16th March, 2012. Discussions focused on several main themes including the effects of CMV on adaptive immunity and immunosenescence, characterization of CMV-specific T cells, impact of CMV infection and ageing on innate immunity, and finally, most important, the clinical implications of immunosenescence and CMV infection. Here we summarize the major findings of this workshop.application/pdfeng© 2012 Solana et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Immunitat cel·lularinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1186/1742-4933-9-23info:eu-repo/semantics/openAccess