Roldán-Espínola, LorenzoVilagut Saiz, Gemma, 1975-Alayo, ItxasoBallester, LauraBlasco Cubedo, Maria JesúsMortier, PhilippeAlonso Caballero, JordiGili, Margalida2025-04-012025-04-012024Roldán-Espínola L, Riera-Serra P, Roca M, García-Toro M, Coronado-Simsic V, Castro A, et al. Depression and lifestyle among university students: A one-year follow-up study. The European Journal of Psychiatry. 2024;38(3):100250. DOI: 10.1016/j.ejpsy.2024.1002500213-6163http://hdl.handle.net/10230/70060Background and objectives: University stage is a risk period for development of mental disorders and major depression disorder (MDD) is one of the most prevalent disorders. There is increasing evidence about the influence of lifestyle factors on depression onset and maintenance, nevertheless there is a great heterogeneity between analyzed lifestyle factors and few longitudinal studies has been carried out. The current study aims to longitudinally assess the influence of lifestyle on MDD courses among first-year university students. Methods: First-onset and persistence of MDD and lifestyle trajectories are measured using baseline and 12-months follow-up online surveys. Multivariate logistic regression analyses were performed to study longitudinal risk/protective associations between lifestyle factors and MDD. Results: 1,292 participants were included. Mean age of included participants at baseline was 18.5 (SD= 1.16) and 75.7 % were female. First-onset and persistence of MDD at T2 were 10.3 % and 38.9 % respectively. Maintenance of healthy sleep (Adjusted Odds Ratio (aOR) = 0.26; 95 % CI =0.12–0.58) and physical activity (aOR = 0.24; 95 % CI = 0.10–0.58) were protectively associated against MDD first-onset. Adoption of healthy levels of social support showed a protective effect against MDD persistence (aOR = 0.17; 95 % CI = 0.07–0.44). Conclusions: Lifestyle should be considered in order to improve depression prevention strategies among university students. Sleep, physical activity, and social support seem to have a crucial role in the onset and persistence of depression among this population.application/pdfeng© 2024 The Authors. Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Psiquiatría y Salud Mental. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://doi.org/10.1016/j.ejpsy.2024.100250DepressionMajor depression disorderLifestyle medicineUniversityUniversity studentsinfo:eu-repo/semantics/openAccess