Roberto, NataliaToll Privat, AlbaElices, MatildePérez Solá, VictorGrande, Iria2025-04-072025-04-072023Roberto N, Vazquez M, Radua J, Pariente JC, Muñoz-Moreno E, Laredo C, et al. Safety intervention for improving functioning in suicidal attempters (STRONG): A secondary prevention study. Study rationale and research protocol. Span J Psychiatry Ment Health. 2023 Aug 25:S2950-2853(23)00001-7. DOI: 10.1016/j.sjpmh.2023.05.0012950-2853http://hdl.handle.net/10230/70094Data de publicació electrònica: 07-09-2023Background: Suicide is one of the most largely preventable causes of death worldwide. The aim of the STRONG study is to assess the effectiveness of a specific intervention (an extended Safety Planning Intervention) called iFightDepression-SURVIVE (iFD-S) in suicidal attempters by changes in psychosocial functioning. As secondary outcomes, quality of life, cognitive performance, clinical state and neuroimaging correlates will be considered. Objective: To describe the rationale and design of the STRONG study, an extension of the SURVIVE study, a national multicenter cohort about on prevention in suicidal attempters. Methods: The STRONG study is a two-year clinical trial. A total sample of 60 patients will be randomly allocated to two arms: a group will receive a iFD-S and treatment as usual (TAU) (n=30 treatment group), while another group will exclusively receive TAU (n=30 control group). There will be three study points: baseline; 3-month; and 6-month follow-up assessments, all of which will include rater-blinded evaluation of psychosocial functioning, quality of life, clinical state, cognitive performance and neuroimaging acquisition. Results: It is expected to obtain data on the efficacy of iFD-S in patients who have committed a suicide attempt. Conclusion: Results will provide insight into the effectiveness of IFD-S in suicidal attempters with respect to improvements in psychosocial functioning, quality of life, cognition, and neuroimaging correlates. Clinical trials id: NCT05655390.application/pdfeng© 2023 The Authors. Published by Elsevier España, S.L.U. on behalf of Sociedad Española de Psiquiatría y Salud Mental (SEPSM). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.sjpmh.2023.05.001Clinical statusCognitionNeuroimagingProtocolPsychosocial functionalityQuality of lifeSafety interventionSuicideinfo:eu-repo/semantics/openAccess