Green CURIOCITY: a study protocol for a European birth cohort study analysing childhood heat-related health impacts and protective effects of urban natural environments

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  • dc.contributor.author van den Bosch, Matilda A.
  • dc.contributor.author Basagaña Flores, Xavier
  • dc.contributor.author Mudu, Pierpaolo
  • dc.contributor.author Kendrovski, Vladimir
  • dc.contributor.author Maitre, Léa
  • dc.contributor.author Hjertager Krog, Norun
  • dc.contributor.author Marit Aasvang, Gunn
  • dc.contributor.author Gražulevičienė, Regina
  • dc.contributor.author McEachan, Rosemary R.C.
  • dc.contributor.author Vrijheid, Martine
  • dc.contributor.author Nieuwenhuijsen, Mark J.
  • dc.date.accessioned 2022-04-28T05:48:43Z
  • dc.date.available 2022-04-28T05:48:43Z
  • dc.date.issued 2022
  • dc.description.abstract Introduction: The European climate is getting warmer and the impact on childhood health and development is insufficiently understood. Equally, how heat-related health risks can be reduced through nature-based solutions, such as exposure to urban natural environments, is unknown. Green CURe In Outdoor CITY spaces (Green CURIOCITY) will analyse how heat exposure during pregnancy affects birth outcomes and how long-term heat exposure may influence children's neurodevelopment. We will also investigate if adverse effects can be mitigated by urban natural environments. A final goal is to visualise intraurban patterns of heat vulnerability and assist planning towards healthier cities. Methods and analysis: We will use existing data from the Human Early-Life Exposure cohort, which includes information on birth outcomes and neurodevelopment from six European birth cohorts. The cohort is linked to data on prenatal heat exposure and impact on birth outcomes will be analysed with logistic regression models, adjusting for air pollution and noise and sociobehavioural covariates. Similarly, impact of cumulative and immediate heat exposure on neurodevelopmental outcomes at age 5 will be assessed. For both analyses, the potentially moderating impact of natural environments will be quantified. For visualisation, Geographical information systems data will be combined to develop vulnerability maps, demonstrating urban 'hot spots' where the risk of negative impacts of heat is aggravated due to sociodemographic and land use patterns. Finally, geospatial and meteorological data will be used for informing GreenUr, an existing software prototype developed by the WHO Regional Office for Europe to quantify health impacts and augment policy tools for urban green space planning. Ethics and dissemination: The protocol was approved by the Comité Ético de Investigación Clínica Parc de Salut MAR, Spain. Findings will be published in peer-reviewed journals and presented at policy events. Through stakeholder engagement, the results will also reach user groups and practitioners.
  • dc.description.sponsorship This work is supported by the European Commission through a Horizon 2020 Marie Skłodowska-Curie Grant, Reference number 891 538.LM is funded by a Juan de la Cierva-Incorporación fellowship (IJC2018-035394-I) awarded by the Spanish Ministerio de Economía, Industria y Competitividad.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation van den Bosch M, Basagaña X, Mudu P, Kendrovski V, Maitre L, Hjertager Krog N, Aasvang GM, Grazuleviciene R, McEachan R, Vrijheid M, Nieuwenhuijsen MJ. Green CURIOCITY: a study protocol for a European birth cohort study analysing childhood heat-related health impacts and protective effects of urban natural environments. BMJ Open. 2022 Jan 24;12(1):e052537. DOI: 10.1136/bmjopen-2021-052537
  • dc.identifier.doi http://dx.doi.org/10.1136/bmjopen-2021-052537
  • dc.identifier.issn 2044-6055
  • dc.identifier.uri http://hdl.handle.net/10230/52921
  • dc.language.iso eng
  • dc.publisher BMJ Publishing Group
  • dc.relation.ispartof BMJ Open. 2022 Jan 24;12(1):e052537
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/891538
  • dc.rights © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri https://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Community child health
  • dc.subject.keyword Epidemiology
  • dc.subject.keyword Preventive medicine
  • dc.subject.keyword Public health
  • dc.title Green CURIOCITY: a study protocol for a European birth cohort study analysing childhood heat-related health impacts and protective effects of urban natural environments
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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