Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography

Gonzalez-Tendero, Anna; Zhang, Chong; Balicevic, Vedrana; Cárdenes, Rubén; Loncaric, Sven; Butakoff, Constantine; Paun, Bruno; Bonnin, Anne; Garcia Canadilla, Patricia; Muñoz-Moreno, Emma; Gratacós Solsona, Eduard; Crispi Brillas, Fàtima; Bijnens, Bart

Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography

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dc.contributor.author Gonzalez-Tendero, Anna
dc.contributor.author Zhang, Chong
dc.contributor.author Balicevic, Vedrana
dc.contributor.author Cárdenes, Rubén
dc.contributor.author Loncaric, Sven
dc.contributor.author Butakoff, Constantine
dc.contributor.author Paun, Bruno
dc.contributor.author Bonnin, Anne
dc.contributor.author Garcia Canadilla, Patricia
dc.contributor.author Muñoz-Moreno, Emma
dc.contributor.author Gratacós Solsona, Eduard
dc.contributor.author Crispi Brillas, Fàtima
dc.contributor.author Bijnens, Bart
dc.date.accessioned 2019-03-26T11:02:01Z
dc.date.available 2019-03-26T11:02:01Z
dc.date.issued 2017
dc.description.abstract While individual cardiac myocytes only have a limited ability to shorten, the heart efficiently pumps a large volume-fraction thanks to a cell organization in a complex 3D fibre structure. Subclinical subtle cardiac structural remodelling is often present before symptoms arise. Understanding and early detection of these subtle changes is crucial for diagnosis and prevention. Additionally, personalized computational modelling requires knowledge on the multi-scale structure of the whole heart and vessels.
dc.description.sponsorship This study was partly supported by Ministerio de Economia y Competitividad (SAF2012-37196;TIN2014-52923-R); Instituto de Salud Carlos III (PI11/00051, PI11/01709, PI12/00801, PI14/00226) integrados en el Plan Nacional de I + D+I y cofinanciados por el ISCIII-Subdirección General de Evaluación y el Fondo Europeo de Desarrollo Regional (FEDER) ‘Otra manera de hacer Europa’; the EU-FP7 for research, technological development and demonstration under grant agreement VP2HF (no611823); The Cerebra Foundation for the Brain Injured Child (Carmarthen, UK); Obra Social ‘la Caixa’ (Barcelona, Spain); Fundació Mutua Madrileña and Fundació Agrupació Mutua (Spain).
dc.format.mimetype application/pdf
dc.identifier.citation Gonzalez-Tendero A, Zhang C, Balicevic V, Cárdenes R, Loncaric S, Butakoff C, Paun B, Bonnin A, Garcia-Cañadilla P, Muñoz-Moreno E, Gratacós E, Crispi F, Bijnens B. Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography. Eur Heart J Cardiovasc Imaging. 2017 Jul 1;18(7):732-41. DOI: 10.1093/ehjci/jew314
dc.identifier.doi http://dx.doi.org/10.1093/ehjci/jew314
dc.identifier.issn 2047-2404
dc.identifier.uri http://hdl.handle.net/10230/36969
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartof European Heart Journal: Cardiovascular Imaging. 2017 Jul 1;18(7):732-41
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/SAF2012-37196
dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/TIN2014-52923-R
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/611823
dc.rights © Oxford University Press. This is a pre-copyedited, author-produced version of an article accepted for publication in European Heart Journal Cardiovascular Imaging following peer review. The version of record Gonzalez-Tendero A, Zhang C, Balicevic V, Cárdenes R, Loncaric S, Butakoff C, Paun B, Bonnin A, Garcia-Cañadilla P, Muñoz-Moreno E, Gratacós E, Crispi F, Bijnens B. Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography. Eur Heart J Cardiovasc Imaging. 2017 Jul 1;18(7):732-41 is available online at: https://dx.doi.org/10.1093/ehjci/jew314
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.subject.keyword Myocardial remodelling
dc.subject.keyword Myofibre structure
dc.subject.keyword Coronary vasculature
dc.subject.keyword Synchrotron phase-contrast CT
dc.title Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/acceptedVersion

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