Ceftolozane-tazobactam: when, how and why using it?

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  • dc.contributor.author López Montesinos, Inmaculada
  • dc.contributor.author Montero, Maria Milagro
  • dc.contributor.author Sorli Redó, M. Luisa
  • dc.contributor.author Horcajada Gallego, Juan Pablo
  • dc.date.accessioned 2022-07-07T06:35:57Z
  • dc.date.available 2022-07-07T06:35:57Z
  • dc.date.issued 2021
  • dc.description.abstract Ceftolozane-tazobactam is currently the most active antipseudomonal agent, including multidrug-resistant extensively drug-resistant strains. Tazobactam provides additional activity against many extended-spectrum beta-lactamases Enterobacterales. Ceftolozane-tazobactam is formally approved for complicated urinary tract infection, complicated intra-abdominal infection, and hospital-acquired and ventilator-associated bacterial pneumonia. The clinical and microbiological success is over 70-80% in many series. However, resistant mutants to ceftolozane-tazobactam have been already described. Combination therapies with colistin or meropenem could be among the strategies to avoid the resistance emergence.en
  • dc.format.mimetype application/pdf
  • dc.identifier.citation López Montesinos I, Montero M, Sorlí L, Horcajada JP. Ceftolozane-tazobactam: when, how and why using it? Rev Esp Quimioter. 2021 Sep; 34 Suppl 1(Suppl1):35-7. DOI: 10.37201/req/s01.10.2021
  • dc.identifier.doi http://dx.doi.org/10.37201/req/s01.10.2021
  • dc.identifier.issn 0214-3429
  • dc.identifier.uri http://hdl.handle.net/10230/53689
  • dc.language.iso eng
  • dc.publisher Sociedad Española de Quimioterapia
  • dc.rights Copyright © The Author 2021. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(http://creativecommons.org/licenses/by-nc/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
  • dc.subject.keyword Anti-Bacterial Agentsen
  • dc.subject.keyword Cephalosporinsen
  • dc.subject.keyword Ceftolozaneen
  • dc.subject.keyword Tazobactamen
  • dc.subject.keyword Colistinen
  • dc.title Ceftolozane-tazobactam: when, how and why using it?en
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion