Structural and functional properties of genes involved in human cancer
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- dc.contributor.author Furney, Simon J.ca
- dc.contributor.author Higgins, Desmond G.ca
- dc.contributor.author Ouzounis, Christos A.ca
- dc.contributor.author López Bigas, Núriaca
- dc.date.accessioned 2012-05-09T07:32:14Z
- dc.date.available 2012-05-09T07:32:14Z
- dc.date.issued 2006ca
- dc.description.abstract Background: One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer./nResults: We have conducted an analysis of a set of genes known to be involved in cancer in order to unveil their unique features that can assist towards the identification of new candidate cancer genes. Conclusion: We have detected key patterns in this group of genes in terms of the molecular function or the biological process in which they are involved as well as sequence properties. Based on these features we have developed an accurate Bayesian classification model with which human genes have been scored for their likelihood of involvement in cancer.
- dc.format.mimetype application/pdfca
- dc.identifier.citation Furney SJ, Higgins DG, Ouzounis CA, López-Bigas N. Structural and functional properties of genes involved in human cancer. BMC Genomics. 2006;7:3. DOI: 10.1186/1471-2164-7-3ca
- dc.identifier.doi http://dx.doi.org/10.1186/1471-2164-7-3
- dc.identifier.issn 1471-2164ca
- dc.identifier.uri http://hdl.handle.net/10230/16420
- dc.language.iso engca
- dc.publisher BioMed Centralca
- dc.relation.ispartof BMC Genomics. 2006;7:3
- dc.rights © 2006 Furney et al. Creative Commons Attribution Licenseca
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/2.0/
- dc.subject.other Càncer -- Aspectes genètics
- dc.subject.other Genètica molecular
- dc.title Structural and functional properties of genes involved in human cancerca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersion