ICU-acquired pneumonia is associated with poor health post-COVID-19 syndrome

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• dc.contributor.author Martin-Loeches, Ignacio
• dc.contributor.author Marín Corral, Judith
• dc.contributor.author Torres, Antoni
• dc.date.accessioned 2022-09-29T07:05:36Z
• dc.date.available 2022-09-29T07:05:36Z
• dc.date.issued 2021
• dc.description.abstract Background: Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to non-critically ill patients, less is known about the incidence and factors associated with the characteristics of persistent COVID-19. On the other hand, these patients very often have intensive care unit-acquired pneumonia (ICUAP). A second infectious hit after COVID increases the length of ICU stay and mechanical ventilation and could have an influence on poor health post-COVID 19 syndrome in ICU-discharged patients. Methods: This prospective, multicentre, and observational study was carrid out across 40 selected ICUs in Spain. Consecutive patients with COVID-19 requiring ICU admission were recruited and evaluated three months after hospital discharge. Results: A total of 1255 ICU patients were scheduled to be followed up at 3 months; however, the final cohort comprised 991 (78.9%) patients. A total of 315 patients developed ICUAP (97% of them had ventilated ICUAP). Patients requiring invasive mechanical ventilation had more persistent post-COVID-19 symptoms than those who did not require mechanical ventilation. Female sex, duration of ICU stay, development of ICUAP, and ARDS were independent factors for persistent poor health post-COVID-19. Conclusions: Persistent post-COVID-19 symptoms occurred in more than two-thirds of patients. Female sex, duration of ICU stay, development of ICUAP, and ARDS all comprised independent factors for persistent poor health post-COVID-19. Prevention of ICUAP could have beneficial effects in poor health post-COVID-19.
• dc.format.mimetype application/pdf
• dc.identifier.citation Martin-Loeches I, Motos A, Menéndez R, Gabarrús A, González J, Fernández-Barat L et al. ICU-acquired pneumonia is associated with poor health post-COVID-19 syndrome. J Clin Med. 2021 Dec 31;11(1):224. DOI: 10.3390/jcm11010224
• dc.identifier.doi http://dx.doi.org/10.3390/jcm11010224
• dc.identifier.issn 2077-0383
• dc.identifier.uri http://hdl.handle.net/10230/54204
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof J Clin Med. 2021 Dec 31;11(1):224
• dc.rights © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri https://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword COVID-19
• dc.subject.keyword CT abnormalities
• dc.subject.keyword ICU
• dc.subject.keyword SARS-CoV-2
• dc.subject.keyword Lung function
• dc.subject.keyword Post-COVID
• dc.subject.keyword Sequelae
• dc.title ICU-acquired pneumonia is associated with poor health post-COVID-19 syndrome
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion