Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of 2 population-based cohorts

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• dc.contributor.author Carsin, Anne-Elie
• dc.contributor.author Guerra, Stefano
• dc.contributor.author García Aymerich, Judith
• dc.date.accessioned 2021-04-20T06:21:15Z
• dc.date.issued 2020
• dc.description.abstract We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were assessed in 2 population-based European cohorts (European Community Respiratory Health Survey: n = 2,757, aged 39-67 years; and Swiss Study on Air Pollution and Lung and Heart Diseases in Adults: n = 2,610, aged 36-82 years) first in 2000-2002 and again approximately 10 years later (2010-2013). Subjects with restrictive or obstructive spirometry pattern at baseline were excluded. We assessed the association of being active at baseline (defined as being physically active at least 2-3 times/week for ≥1 hour) with restrictive spirometry pattern at follow-up (defined as a postbronchodilation FEV1/FVC ratio of at least the lower limit of normal and FVC of <80% predicted) using modified Poisson regression, adjusting for relevant confounders. After 10 years of follow-up, 3.3% of participants had developed restrictive spirometry pattern. Being physically active was associated with a lower risk of developing this phenotype (relative risk = 0.76, 95% confidence interval: 0.59, 0.98). This association was stronger among those who were overweight and obese than among those of normal weight (P for interaction = 0.06). In 2 large European studies, adults practicing regular physical activity were at lower risk of developing restrictive spirometry pattern over 10 years.
• dc.description.sponsorship This work was supported by the Ageing Lungs in European Cohorts (ALEC) Study (www.alecstudy.org), which has received funding from the European Union’s Horizon 2020 research and innovation program (grant 633212). Swiss Studyon Air Pollution and Lung and Heart Diseases in Adults is funded by the National Science Foundation (grant 33CS30-177506)
• dc.format.mimetype application/pdf
• dc.identifier.citation Carsin A, Guerra S, Garcia-Aymerich J. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of 2 population-based cohorts. Am J Epidemiol. 2020 Dec 1; 189(12): 1521-1528. DOI: 10.1093/aje/kwaa087
• dc.identifier.doi http://dx.doi.org/10.1093/aje/kwaa087
• dc.identifier.issn 0002-9262
• dc.identifier.uri http://hdl.handle.net/10230/47151
• dc.language.iso eng
• dc.publisher Oxford University Press
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/633212
• dc.rights © Oxford University Press. This is a pre-copyedited, author-produced version of an article accepted for publication in American Journal of Epidemiology following peer review. The version of record Carsin A, Guerra S, Garcia-Aymerich J. Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of 2 population-based cohorts. Am J Epidemiol. 2020 Dec 1; 189(12): 1521-1528 is available online at: http://dx.doi.org/10.109/aje/kwaa087
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.other Exercici
• dc.subject.other Espirometria
• dc.title Regular physical activity levels and incidence of restrictive spirometry pattern: a longitudinal analysis of 2 population-based cohorts
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion