Incremental cost of nosocomial bacteremia according to the focus of infection and antibiotic sensitivity of the causative microorganism in a university hospital

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  • dc.contributor.author Riu Camps, Martaca
  • dc.contributor.author Chiarello, Pietroca
  • dc.contributor.author Terradas Robledo, Roserca
  • dc.contributor.author Sala Serra, Mariaca
  • dc.contributor.author Garcia-Alzorriz, Enricca
  • dc.contributor.author Castells, Xavierca
  • dc.contributor.author Grau Cerrato, Santiagoca
  • dc.contributor.author Cots Reguant, Francescca
  • dc.date.accessioned 2018-06-28T07:07:18Z
  • dc.date.available 2018-06-28T07:07:18Z
  • dc.date.issued 2017
  • dc.description.abstract To estimate the incremental cost of nosocomial bacteremia according to the causative focus and classified by the antibiotic sensitivity of the microorganism.Patients admitted to Hospital del Mar in Barcelona from 2005 to 2012 were included. We analyzed the total hospital costs of patients with nosocomial bacteremia caused by microorganisms with a high prevalence and, often, with multidrug-resistance. A control group was defined by selecting patients without bacteremia in the same diagnosis-related group.Our hospital has a cost accounting system (full-costing) that uses activity-based criteria to estimate per-patient costs. A logistic regression was fitted to estimate the probability of developing bacteremia (propensity score) and was used for propensity-score matching adjustment. This propensity score was included in an econometric model to adjust the incremental cost of patients with bacteremia with differentiation of the causative focus and antibiotic sensitivity.The mean incremental cost was estimated at &OV0556;15,526. The lowest incremental cost corresponded to bacteremia caused by multidrug-sensitive urinary infection (&OV0556;6786) and the highest to primary or unknown sources of bacteremia caused by multidrug-resistant microorganisms (&OV0556;29,186).This is one of the first analyses to include all episodes of bacteremia produced during hospital stays in a single study. The study included accurate information about the focus and antibiotic sensitivity of the causative organism and actual hospital costs. It provides information that could be useful to improve, establish, and prioritize prevention strategies for nosocomial infections
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Riu M, Chiarello P, Terradas R, Sala M, Garcia-Alzorriz E, Castells X. et al. Incremental cost of nosocomial bacteremia according to the focus of infection and antibiotic sensitivity of the causative microorganism in a university hospital. Medicine (Baltimore). 2017 Apr;96(17):e6645. DOI: 10.1097/MD.0000000000006645
  • dc.identifier.doi http://dx.doi.org/10.1097/MD.0000000000006645
  • dc.identifier.issn 0025-7974
  • dc.identifier.uri http://hdl.handle.net/10230/34985
  • dc.language.iso eng
  • dc.publisher Lippincott Williams & Wilkinsca
  • dc.relation.ispartof Medicine (Baltimore). 2017 Apr;96(17):e6645
  • dc.rights Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0
  • dc.subject.other Bacterièmia
  • dc.subject.other Infeccions nosocomials
  • dc.title Incremental cost of nosocomial bacteremia according to the focus of infection and antibiotic sensitivity of the causative microorganism in a university hospitalca
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion