CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

Griffith, Malachi; López Bigas, Núria; Griffith, Obi L.

doi:http://dx.doi.org/10.1038/ng.3774

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

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Griffith M, Spies NC, Krysiak K, McMichael JF, Coffman AC, Danos AM et al. CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. Nat Genet. 2017; 49(2):170-4. DOI: 10.1038/ng.3774

Abstract

CIViC is an expert-crowdsourced knowledgebase for Clinical Interpretation of Variants in Cancer describing the therapeutic, prognostic, diagnostic and predisposing relevance of inherited and somatic variants of all types. CIViC is committed to open-source code, open-access content, public application programming interfaces (APIs) and provenance of supporting evidence to allow for the transparent creation of current and accurate variant interpretations for use in cancer precision medicine.