Understanding the genomic heterogeneity of North African Imazighen: from broad to microgeographical perspectives

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  • dc.contributor.author Vilà Valls, Laura
  • dc.contributor.author Abdeli, Amine
  • dc.contributor.author Lucas Sánchez, Marcel
  • dc.contributor.author Bekada, Asmahan
  • dc.contributor.author Calafell i Majó, Francesc
  • dc.contributor.author Benhassine, Traki
  • dc.contributor.author Comas, David, 1969-
  • dc.date.accessioned 2024-06-13T06:22:00Z
  • dc.date.available 2024-06-13T06:22:00Z
  • dc.date.issued 2024
  • dc.description.abstract The strategic location of North Africa has led to cultural and demographic shifts, shaping its genetic structure. Historical migrations brought different genetic components that are evident in present-day North African genomes, along with autochthonous components. The Imazighen (plural of Amazigh) are believed to be the descendants of autochthonous North Africans and speak various Amazigh languages, which belong to the Afro-Asiatic language family. However, the arrival of different human groups, especially during the Arab conquest, caused cultural and linguistic changes in local populations, increasing their heterogeneity. We aim to characterize the genetic structure of the region, using the largest Amazigh dataset to date and other reference samples. Our findings indicate microgeographical genetic heterogeneity among Amazigh populations, modeled by various admixture waves and different effective population sizes. A first admixture wave is detected group-wide around the twelfth century, whereas a second wave appears in some Amazigh groups around the nineteenth century. These events involved populations with higher genetic ancestry from south of the Sahara compared to the current North Africans. A plausible explanation would be the historical trans-Saharan slave trade, which lasted from the Roman times to the nineteenth century. Furthermore, our investigation shows that assortative mating in North Africa has been rare.
  • dc.description.sponsorship This work was funded by MICIU/AEI/https://doi.org/10.13039/501100011033/ ERF A way of making Europe (grant numbers I-COOP0018; PID2019-106485GB-I00 and PID2022-138755NB-I00).
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Vilà-Valls L, Abdeli A, Lucas-Sánchez M, Bekada A, Calafell F, Benhassine T, et al. Understanding the genomic heterogeneity of North African Imazighen: from broad to microgeographical perspectives. Sci Rep. 2024 May 1;14(1):9979. DOI: 10.1038/s41598-024-60568-8
  • dc.identifier.doi http://dx.doi.org/10.1038/s41598-024-60568-8
  • dc.identifier.issn 2045-2322
  • dc.identifier.uri http://hdl.handle.net/10230/60453
  • dc.language.iso eng
  • dc.publisher Nature Research
  • dc.relation.ispartof Sci Rep. 2024 May 1;14(1):9979
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/PID2019-106485GB-I00
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/3PE/PID2022-138755NB-I00
  • dc.rights © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Biological anthropology
  • dc.subject.keyword Genetic variation
  • dc.title Understanding the genomic heterogeneity of North African Imazighen: from broad to microgeographical perspectives
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion