Relationship between genome and epigenome - challenges and requirements for future research

Almouzni, Geneviève; Estivill, Xavier, 1955-; Ossowski, Stephan; Widschwendter, Martin

doi:http://dx.doi.org/10.1186/1471-2164-15-487

Relationship between genome and epigenome - challenges and requirements for future research

License

Citation

Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N et al. Relationship between genome and epigenome - challenges and requirements for future research. BMC Genomics. 2014; 15: 487. DOI 10.1186/1471-2164-15-487

Abstract

Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.