Software for predicting the 3D structure of RNA molecules

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• dc.contributor.author Dufour, Davidca
• dc.contributor.author Martí Renom, Marc A.ca
• dc.date.accessioned 2016-07-26T13:38:07Z
• dc.date.available 2016-07-26T13:38:07Z
• dc.date.issued 2015
• dc.description.abstract RNA is not regarded anymore as a simple transfer molecule between DNA and proteins. Indeed, over the past decades a plethora of new functional roles have been assigned to RNA molecules. Such functions are carried out either by RNA molecules alone or through interactions with DNA, other RNA molecules, or proteins. In all cases, the structure that the RNA molecule adopts will impact its function, as it happens with proteins. Therefore, to fully characterize the function of an RNA molecule, its structure needs to be either determined by experiments or predicted by computation. Unfortunately, our knowledge of the atomic mechanism by which RNA molecules adopt their biological active structures is still limited. Such hurdle is now being addressed by the development of new computational methods for RNA structure prediction, which complement experimental methods such as X-ray crystallography, nuclear magnetic resonance, small-angle X-ray scattering, and cryo-electron microscopy. This software focus is not dedicated to a single computational method but aims at outlining the most adopted methods for computational RNA structure prediction.ca
• dc.format.mimetype application/pdfca
• dc.identifier.citation Dufour D, Marti-Renom MA. Software for predicting the 3D structure of RNA molecules. Wiley interdisciplinary reviews: computational molecular science. 2015; 5(1): 56-61. DOI 10.1002/wcms.1198ca
• dc.identifier.doi http://dx.doi.org/10.1002/wcms.1198
• dc.identifier.issn 1759-0876
• dc.identifier.uri http://hdl.handle.net/10230/27133
• dc.language.iso engca
• dc.publisher Wileyca
• dc.relation.ispartof Wiley interdisciplinary reviews: computational molecular science. 2015; 5(1): 56-61
• dc.rights This is the pre-peer reviewed version of the following article: Dufour D, Marti-Renom MA. Software for predicting the 3D structure of RNA molecules. Wiley interdisciplinary reviews: computational molecular science. 2015; 5(1): 56-61. DOI 10.1002/wcms.1198, which has been published in final form at http://dx.doi.org/10.1002/wcms.1198. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.subject.other RNAca
• dc.subject.other ADNca
• dc.title Software for predicting the 3D structure of RNA moleculesca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/acceptedVersionca