Determinants and outcomes of physical activity in patients with COPD: a systematic review

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  • dc.contributor.author Gimeno Santos, Elena, 1980-ca
  • dc.contributor.author Frei, Anjaca
  • dc.contributor.author Steurer Stey, Claudiaca
  • dc.contributor.author Batlle Garcia, Jordi de, 1981-ca
  • dc.contributor.author Rabinovich, Roberto A.ca
  • dc.contributor.author Raste, Yoginica
  • dc.contributor.author Hopkinson, Nicholas S.ca
  • dc.contributor.author Polkey, Michael I.ca
  • dc.contributor.author van Remoortel, Hansca
  • dc.contributor.author Troosters, Thierryca
  • dc.contributor.author Kulich, Karolyca
  • dc.contributor.author Karlsson, Niklasca
  • dc.contributor.author Puhan, Milo A.ca
  • dc.contributor.author García Aymerich, Judithca
  • dc.contributor.author PROactive consortiumca
  • dc.date.accessioned 2016-05-31T14:07:12Z
  • dc.date.available 2016-05-31T14:07:12Z
  • dc.date.issued 2014
  • dc.description.abstract BACKGROUND: The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise studies assessing associations between physical activity and its determinants and/or outcomes in patients with COPD and to develop a conceptual model for physical activity in COPD. METHODS: We conducted a systematic search of four databases (Medline, Embase, CINAHL and Psychinfo) prior to November 2012. Teams of two reviewers independently selected articles, extracted data and used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to assess quality of evidence. RESULTS: 86 studies were included: 59 were focused on determinants, 23 on outcomes and 4 on both. Hyperinflation, exercise capacity, dyspnoea, previous exacerbations, gas exchange, systemic inflammation, quality of life and self-efficacy were consistently related to physical activity, but often based on cross-sectional studies and low-quality evidence. Results from studies of pharmacological and non-pharmacological treatments were inconsistent and the quality of evidence was low to very low. As outcomes, COPD exacerbations and mortality were consistently associated with low levels of physical activity based on moderate quality evidence. Physical activity was associated with other outcomes such as dyspnoea, health-related quality of life, exercise capacity and FEV1 but based on cross-sectional studies and low to very low quality evidence. CONCLUSIONS: Physical activity level in COPD is consistently associated with mortality and exacerbations, but there is poor evidence about determinants of physical activity, including the impact of treatment.ca
  • dc.description.sponsorship The PROactive project is funded by the European Commission Innovative Medicines Initiative Joint Undertaking (IMI JU # 115011)
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Gimeno-Santos E, Frei A, Steurer-Stey C, de Batlle J, Rabinovich RA, Raste Y et al. Determinants and outcomes of physical activity in patients with COPD: a systematic review. Thorax. 2014; 69(8): 731-739. DOI 10.1136/thoraxjnl-2013-204763ca
  • dc.identifier.doi http://dx.doi.org/10.1136/thoraxjnl-2013-204763
  • dc.identifier.issn 0040-6376
  • dc.identifier.uri http://hdl.handle.net/10230/26787
  • dc.language.iso engca
  • dc.publisher BMJ Publishing Groupca
  • dc.relation.ispartof Thorax. 2014; 69(8): 731-739
  • dc.rights This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.ca
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/3.0/ca
  • dc.subject.keyword COPD Exacerbations
  • dc.subject.keyword COPD epidemiology
  • dc.subject.keyword Exercise
  • dc.subject.other Pulmons -- Malalties obstructivesca
  • dc.subject.other Exercici -- Aspectes fisiològicsca
  • dc.title Determinants and outcomes of physical activity in patients with COPD: a systematic reviewca
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca

Col·leccions

Articles (Barcelona Institute for Global Health (ISGlobal) – Campus Mar)
Articles (Departament de Medicina i Ciències de la Vida)