bwtool: a tool for bigWig files

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  • dc.contributor.author Pohl, Andy, 1979-
  • dc.contributor.author Beato, Miguel
  • dc.date.accessioned 2020-12-02T07:17:22Z
  • dc.date.available 2020-12-02T07:17:22Z
  • dc.date.issued 2014
  • dc.description.abstract BigWig files are a compressed, indexed, binary format for genome-wide signal data for calculations (e.g. GC percent) or experiments (e.g. ChIP-seq/RNA-seq read depth). bwtool is a tool designed to read bigWig files rapidly and efficiently, providing functionality for extracting data and summarizing it in several ways, globally or at specific regions. Additionally, the tool enables the conversion of the positions of signal data from one genome assembly to another, also known as 'lifting'. We believe bwtool can be useful for the analyst frequently working with bigWig data, which is becoming a standard format to represent functional signals along genomes. The article includes supplementary examples of running the software.
  • dc.description.sponsorship Supported by grants to M.B. from the Departament d'Innovació Universitat i Empresa (DIUiE) 2009SGR574, Ministerio de Educación y Ciencia (MEC) BFU2010-01531 and CSD2006-00049.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Pohl A, Beato M. bwtool: a tool for bigWig files. Bioinformatics. 2014; 30(11):1618-9. DOI: 10.1093/bioinformatics/btu056
  • dc.identifier.doi http://dx.doi.org/10.1093/bioinformatics/btu056
  • dc.identifier.issn 1367-4803
  • dc.identifier.uri http://hdl.handle.net/10230/45929
  • dc.language.iso eng
  • dc.publisher Oxford University Press
  • dc.relation.ispartof Bioinformatics. 2014; 30(11):1618-9
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BFU2010-01531
  • dc.rights © The Author 2014. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/3.0/
  • dc.title bwtool: a tool for bigWig files
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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Articles (Departament de Medicina i Ciències de la Vida)
Articles (Center for Genomic Regulation (CRG))