Prevalence of asthma-like symptoms with ageing

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• dc.contributor.author Jarvis, Deborahca
• dc.contributor.author Antó i Boqué, Josep Mariaca
• dc.contributor.author Zock, Jan-Paulca
• dc.contributor.author Burney, Peterca
• dc.date.accessioned 2018-07-27T07:33:11Z
• dc.date.available 2018-07-27T07:33:11Z
• dc.date.issued 2016
• dc.description.abstract BACKGROUND: Change in the prevalence of asthma-like symptoms in populations of ageing adults is likely to be influenced by smoking, asthma treatment and atopy. METHODS: The European Community Respiratory Health Survey collected information on prevalent asthma-like symptoms from representative samples of adults aged 20-44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence were determined using generalised estimating equations (accounting for non-response through inverse probability weighting), followed by meta-analysis of centre level estimates. FINDINGS: Over 20 years the prevalence of 'wheeze' and 'wheeze in the absence of a cold' decreased (-2.4%, 95% CI -3.5 to -1.3%; -1.5%, 95% CI -2.4 to -0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication and hay fever/nasal allergies increased (0.6%, 95% CI 0.1 to 1.11; 3.6%, 95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only). Decreases in these wheeze-related symptoms were largely seen in the group who gave up smoking, and were seen in those who reported hay fever/nasal allergies at baseline. INTERPRETATION: European adults born between 1946 and 1970 have, over the last 20 years, experienced less wheeze, although they were more likely to report asthma attacks, use of asthma medication and hay fever. Decrease in wheeze is largely attributable to smoking cessation, rather than improved treatment of asthma. It may also be influenced by reductions in atopy with ageing.
• dc.format.mimetype application/pdf
• dc.identifier.citation Jarvis D, Newson R, Janson C, Corsico A, Heinrich J, Anto JM et al. Prevalence of asthma-like symptoms with ageing. Thorax. 2018 Jan;73(1):37-48. DOI: 10.1136/thoraxjnl-2016-209596
• dc.identifier.doi http://dx.doi.org/10.1136/thoraxjnl-2016-209596
• dc.identifier.issn 0040-6376
• dc.identifier.uri http://hdl.handle.net/10230/35309
• dc.language.iso eng
• dc.publisher BMJ Publishing Groupca
• dc.relation.ispartof Thorax. 2018 Jan;73(1):37-48
• dc.rights This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Asthma Epidemiology
• dc.subject.other Asma
• dc.subject.other Epidemiologia
• dc.title Prevalence of asthma-like symptoms with ageingca
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion