New advances in CMV and immunosenescence

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• dc.contributor.author Sansoni, Paolo
• dc.contributor.author López-Botet, M. (Miguel)
• dc.contributor.author Muntasell i Castellví, Aura, 1972-
• dc.contributor.author Nikolich Zugich, Janko
• dc.date.accessioned 2025-01-13T08:31:21Z
• dc.date.available 2025-01-13T08:31:21Z
• dc.date.issued 2014
• dc.description.abstract Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiological studies suggest that persistent Cytomegalovirus (CMV) infection is associated with accelerated aging of the immune system and with several age-related diseases. However, current evidence on whether and how human CMV (HCMV) infection is implicated in immunosenescence and in age-related diseases remains incomplete and many aspects of CMV involvement in immune aging remain controversial. The attendees of the 4th International Workshop on “CMV & Immunosenescence”, held in Parma, Italy, 25–27th March, 2013, presented and discussed data related to these open questions, which are reported in this commentary.en
• dc.format.mimetype application/pdf
• dc.identifier.citation Sansoni S, Vescovini R, Fagnoni FF, Akbar A, Arens R, Chiu YL, et al. New advances in CMV and immunosenescence. Exp Gerontol. 2014 Jul;55:54-62. DOI: 10.1016/j.exger.2014.03.020
• dc.identifier.doi http://dx.doi.org/10.1016/j.exger.2014.03.020
• dc.identifier.issn 1873-6815
• dc.identifier.uri http://hdl.handle.net/10230/69055
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Experimental Gerontology. 2014 Jul;55:54-62
• dc.rights © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/
• dc.subject.keyword Immunosenescenceen
• dc.subject.keyword Cytomegalovirus infectionen
• dc.subject.keyword Immune homeostasisen
• dc.subject.keyword Pathologies of agingen
• dc.subject.keyword Virus-host interactionen
• dc.title New advances in CMV and immunosenescence
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion