Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Bosch, Guillermo
• dc.contributor.author Posso, Margarita
• dc.contributor.author Louro, Javier
• dc.contributor.author Román, Marta
• dc.contributor.author Porta Serra, Miquel
• dc.contributor.author Castells, Xavier
• dc.contributor.author Macià Guilà, Francesc Assís
• dc.date.accessioned 2022-10-24T06:35:32Z
• dc.date.available 2022-10-24T06:35:32Z
• dc.date.issued 2022
• dc.description.abstract Background: To assess the effect of the COVID-19 pandemic on performance indicators in the population-based breast cancer screening program of Parc de Salut Mar (PSMAR), Barcelona, Spain. Methods: we conducted a before-and-after, study to evaluate participation, recall, false positives, the cancer detection rate, and cancer characteristics in our screening population from March 2020 to March 2021 compared with the four previous rounds (2012-2019). Using multilevel logistic regression models, we estimated the adjusted odds ratios (aORs) of each of the performance indicators for the COVID-19 period, controlling by type of screening (prevalent or incident), socioeconomic index, family history of breast cancer, and menopausal status. We analyzed 144,779 invitations from 47,571women. Results: during the COVID-19 period, the odds of participation were lower in first-time invitees (aOR = 0.90 [95% CI = 0.84-0.96]) and in those who had previously participated regularly and irregularly (aOR = 0.63 [95% CI = 0.59-0.67] and aOR = 0.95 [95% CI = 0.86-1.05], respectively). Participation showed a modest increase in women not attending any of the previous rounds (aOR = 1.10 [95% CI = 1.01-1.20]). The recall rate decreased in both prevalent and incident screening (aOR = 0.74 [95% CI = 0.56-0.99] and aOR = 0.80 [95% CI = 0.68-0.95], respectively). False positives also decreased in both groups (prevalent aOR = 0.92 [95% CI = 0.66-1.28] and incident aOR = 0.72 [95% CI = 0.59-0.88]). No significant differences were observed in compliance with recall (OR = 1.26, 95% CI = 0.76-2.23), cancer detection rate (aOR = 0.91 [95% CI = 0.69-1.18]), or cancer stages. Conclusions: the COVID-19 pandemic negatively affected screening attendance, especially in previous participants and newcomers. We found a reduction in recall and false positives and no marked differences in cancer detection, indicating the robustness of the program. There is a need for further evaluations of interval cancers and potential diagnostic delays.
• dc.format.mimetype application/pdf
• dc.identifier.citation Bosch G, Posso M, Louro J, Roman M, Porta M, Castells X, et al. Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study. Elife. 2022 Jun 10; 11: e77434. DOI: 10.7554/eLife.77434.
• dc.identifier.doi http://dx.doi.org/10.7554/eLife.77434
• dc.identifier.issn 2050-084X
• dc.identifier.uri http://hdl.handle.net/10230/54547
• dc.language.iso eng
• dc.publisher eLife
• dc.rights Copyright © 2022, Bosch et al. This article is distributed under the terms of the Creative Commons Attribution License, http://creativecommons.org/licenses/by/4.0/ which permits unrestricted use and redistribution provided that the original author and source are credited.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword COVID-19
• dc.subject.keyword Breast neoplasm
• dc.subject.keyword Early detection of cancer
• dc.subject.keyword Epidemiology
• dc.subject.keyword Global health
• dc.subject.keyword Human
• dc.subject.keyword Nonrandomized controlled trials
• dc.subject.keyword Quality indicators
• dc.title Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion