Determinants of health-related quality of life in healthy children and adolescents during the COVID-19 pandemic: Results from a prospective longitudinal cohort study

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• dc.contributor.author Haile, Sarah R.
• dc.contributor.author Peralta, Gabriela P.
• dc.contributor.author Raineri, Alessia
• dc.contributor.author Rueegg, Sonja
• dc.contributor.author Ulyte, Agne
• dc.contributor.author Ulyte, Agne
• dc.contributor.author Puhan, Milo A.
• dc.contributor.author Radtke, Thomas
• dc.contributor.author Kriemler, Susi
• dc.date.accessioned 2024-07-02T06:22:27Z
• dc.date.available 2024-07-02T06:22:27Z
• dc.date.issued 2024
• dc.description.abstract Understanding health-related quality of life (HRQOL) in children and adolescents, during a pandemic and afterwards, aids in understanding how circumstances in their lives impact their well-being. We aimed to identify determinants of HRQOL from a broad range of biological, psychological, and social factors in a large longitudinal population-based sample. Data was taken from a longitudinal sample (n = 1843) of children and adolescents enrolled in the prospective school-based cohort study Ciao Corona in Switzerland. The primary outcome was HRQOL, assessed using the KINDL total score and its subscales (each from 0, worst, to 100, best). Potential determinants, including biological (physical activity, screen time, sleep, etc.), psychological (sadness, anxiousness, stress), and social (nationality, parents' education, etc.) factors, were assessed in 2020 and 2021 and HRQOL in 2022. Determinants were identified in a data-driven manner using recursive partitioning to define homogeneous subgroups, stratified by school level. Median KINDL total score in the empirically identified subgroups ranged from 68 to 83 in primary school children and from 69 to 82 in adolescents in secondary school. The psychological factors sadness, anxiousness, and stress in 2021 were identified as the most important determinants of HRQOL in both primary and secondary school children. Other factors, such as physical activity, screen time, chronic health conditions, or nationality, were determinants only in individual subscales. Conclusion: Recent mental health, more than biological, physical, or social factors, played a key role in determining HRQOL in children and adolescents during pandemic times. Public health strategies to improve mental health may therefore be effective in improving HRQOL in this age group. What is known: • Assessing health-related quality of life (HRQOL) in children and adolescents aids in understanding how life circumstances impact their well-being. • HRQOL is a complex construct, involving biological, psychological, and social factors. Factors driving HRQOL in children and adolescents are not often studied in longitudinal population-based samples. What is new: • Mental health (stress, anxiousness, sadness) played a key role in determining HRQOL during the coronavirus pandemic, more than biological or social factors. • Public health strategies to improve mental health may be effective in improving HRQOL in children.
• dc.format.mimetype application/pdf
• dc.identifier.citation Haile SR, Peralta GP, Raineri A, Rueegg S, Ulytė A, Puhan MA, et al. Determinants of health-related quality of life in healthy children and adolescents during the COVID-19 pandemic: Results from a prospective longitudinal cohort study. Eur J Pediatr. 2024 May;183(5):2273-83. DOI: 10.1007/s00431-024-05459-w
• dc.identifier.doi http://dx.doi.org/10.1007/s00431-024-05459-w
• dc.identifier.issn 0340-6199
• dc.identifier.uri http://hdl.handle.net/10230/60628
• dc.language.iso eng
• dc.publisher Springer
• dc.relation.ispartof Eur J Pediatr. 2024 May;183(5):2273-83
• dc.rights © The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Anxiety
• dc.subject.keyword Depression
• dc.subject.keyword Mental health
• dc.subject.keyword Pandemic
• dc.subject.keyword Physical activity
• dc.subject.keyword Stress
• dc.subject.keyword Well-being
• dc.subject.keyword Youth
• dc.title Determinants of health-related quality of life in healthy children and adolescents during the COVID-19 pandemic: Results from a prospective longitudinal cohort study
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion