Positional information and reaction-diffusion: two big idea in developmental biology combine

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  • dc.contributor.author Green, Jeremy B.A.ca
  • dc.contributor.author Sharpe, Jamesca
  • dc.date.accessioned 2015-11-09T19:30:13Z
  • dc.date.available 2015-11-09T19:30:13Z
  • dc.date.issued 2015
  • dc.description.abstract One of the most fundamental questions in biology is that of biological pattern: how do the structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in this area are those of Alan Turing’s ‘reaction-diffusion’ and Lewis Wolpert’s ‘positional information’. Much has been written about these two concepts but some confusion still remains, in particular about the relationship between them. Here, we address this relationship and propose a scheme of three distinct ways in which these two ideas work together to shape biological form.en
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Green JB, Sharpe J. Positional information and reaction-diffusion: two big idea in developmental biology combine. Development. 2015; 142(7): 1203-1211. DOI 10.1242/dev.114991ca
  • dc.identifier.doi http://dx.doi.org/10.1242/dev.114991
  • dc.identifier.issn 0950-1991
  • dc.identifier.uri http://hdl.handle.net/10230/25028
  • dc.language.iso engca
  • dc.publisher Company of Biologists (J Experimental Biology)ca
  • dc.relation.ispartof Development. 2015; 142(7): 1203-1211
  • dc.rights © 2015. Published by The Company of Biologists Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.en
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri http://creativecommons.org/licenses/by/3.0ca
  • dc.subject.keyword Reaction-diffusionen
  • dc.subject.keyword Biological patternen
  • dc.subject.keyword Developmental biologyen
  • dc.subject.keyword History of ideasen
  • dc.subject.other Imatges, Sistemes d'ca
  • dc.subject.other Biologia del desenvolupamentca
  • dc.title Positional information and reaction-diffusion: two big idea in developmental biology combineen
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca