Cilia control fat deposition during tissue repair
Cilia control fat deposition during tissue repair
Citació
- Perdiguero E, Serrano AL, Muñoz-Cánoves P. Cilia control fat deposition during tissue repair. Dev Cell. 2017;42(2):114-6. DOI: 10.1016/j.devcel.2017.06.023
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Descripció
Resum
Fibro/adipogenic progenitors (FAPs) are emerging as crucial regulators of fibrous and fat deposits during skeletal muscle regeneration. In a recent issue of Cell, Kopinke et al. (2017) report that primary cilia induce the adipogenic fate of FAPs in injured and diseased muscle by restraining Hedgehog signaling.