IntOGen-mutations identifies cancer drivers across tumor types

Gonzalez-Perez, Abel; Pérez Llamas, Christian, 1976-; Deu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp,1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria

doi:http://dx.doi.org/10.1038/nmeth.2642

IntOGen-mutations identifies cancer drivers across tumor types

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Gonzalez-Perez A, Perez-Llamas C, Deu-Pons J, Tamborero D, Schroeder MP, Jene-Sanz A, et al. IntOGen-mutations identifies cancer drivers across tumor types. Nat Methods. 2013 Nov;10(11):1081-2. DOI: 10.1038/nmeth.2642

Abstract

The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making.