Residential relocation to assess impact of changes in the living environment on cardio-respiratory health: a narrative literature review with considerations for exposome research

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• dc.contributor.author Saucy, Apolline
• dc.contributor.author Ortega, Natalia
• dc.contributor.author Tonne, Cathryn
• dc.date.accessioned 2024-03-25T06:52:58Z
• dc.date.available 2024-03-25T06:52:58Z
• dc.date.issued 2024
• dc.description Includes supplementary materials for the online appendix.
• dc.description.abstract Residential relocation studies have become increasingly valuable tools for evaluating the effects of changing living environments on human health, but little is known about their application to multiple aspects of the living environment and the most appropriate methodology. This narrative review explores the utility of residential relocation as a natural experiment for studying the impact of changing urban exposures on cardio-metabolic health in high-income settings. It provides a comprehensive overview of the use of residential relocation studies, evaluates their methodological approaches, and synthesizes findings related to health behaviors and cardio-metabolic outcomes. Our search identified 43 relevant studies published between January 1995 and February 2023, from eight countries, predominantly the USA, Canada, and Australia. The majority of eligible studies were published between 2012 and 2021 and examined changes in various domains of the living environment, such as walkability, the built and social environments, but rarely combinations of exposures. Included studies displayed heterogeneity in design and outcomes, 25 involving only movers and 18 considering both movers and non-movers. To mitigate the issue of residential self-selection bias, most studies employed a “change-in-change” design and adjusted for baseline covariates but only a fraction of them accounted for time-varying confounding. Relocation causes simultaneous changes in various features of the living environment, which presents an opportunity for exposome research to establish causal relationships, using large datasets with increased statistical power and a wide range of health outcomes, behaviors and biomarkers. Residential relocation is not a random process. Thus, studies focusing on living environment characteristics need to carefully select time-varying covariates and reference group. Overall, this review informs future research by guiding choices in study design, data requirements, and statistical methodologies. Ultimately, it contributes to the advancement of the urban exposome field and enhances our understanding of the complex relationship between urban environments and human health.
• dc.description.sponsorship The EXPANSE project is funded by the European Union's Horizon 2020 research and innovation programme under grand agreement No 874627. AS has received funding from the Swiss National Science Foundation (grant number 210781). We acknowledge support from the Spanish Ministry of Science and Innovation and State Research Agency through the “Centro de Excelencia Severo Ochoa 2019–2023” Program (CEX 2018-000806-S) and from the Generalitat de Catalunya through the CERCA Program.
• dc.format.mimetype application/pdf
• dc.identifier.citation Saucy A, Ortega N, Tonne C. Residential relocation to assess impact of changes in the living environment on cardio-respiratory health: a narrative literature review with considerations for exposome research. Environmental Research. 2024 Mar 1;244:117890. DOI: 10.1016/j.envres.2023.117890
• dc.identifier.doi http://dx.doi.org/10.1016/j.envres.2023.117890
• dc.identifier.issn 0013-9351
• dc.identifier.uri http://hdl.handle.net/10230/59536
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Environmental Research. 2024 Mar 1;244:117890
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/874627
• dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/CEX2018-000806-S
• dc.rights © 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Residential relocation
• dc.subject.keyword Living environments
• dc.subject.keyword Exposome
• dc.subject.keyword Natural experiments
• dc.subject.keyword Movers
• dc.subject.keyword Cardiorespiratory health
• dc.title Residential relocation to assess impact of changes in the living environment on cardio-respiratory health: a narrative literature review with considerations for exposome research
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion