Mutations make gut antibodies promiscuous

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dc.contributor.authorGrasset, Emilie K.
dc.contributor.authorCerutti, Andrea, 1965-
dc.date.accessioned2021-11-04T07:38:23Z
dc.date.available2021-11-04T07:38:23Z
dc.date.issued2020
dc.description.abstractIn this issue, Kabbert et al. (https://doi.org/10.1084/jem.20200275) show that intestinal antibodies from healthy subjects or patients with Crohn's disease cross-target diverse but distinct communities of the gut microbiota through a mechanism involving somatic hypermutation but not germline-encoded polyreactivity.
dc.format.mimetypeapplication/pdf
dc.identifier.citationGrasset EK, Cerutti A. Mutations make gut antibodies promiscuous. J Exp Med. 2020 Nov 2; 217(11): e20201340. DOI: 10.1084/jem.20201340
dc.identifier.doihttp://dx.doi.org/10.1084/jem.20201340
dc.identifier.issn0022-1007
dc.identifier.urihttp://hdl.handle.net/10230/48899
dc.language.isoeng
dc.publisherRockefeller University Press
dc.rightsThis article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/)
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject.otherImmunoglobulines
dc.subject.otherIntestins--Microbiologia
dc.subject.otherCrohn, Malaltia de
dc.titleMutations make gut antibodies promiscuous
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion

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