Mutations make gut antibodies promiscuous

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  • dc.contributor.author Grasset, Emilie K.
  • dc.contributor.author Cerutti, Andrea, 1965-
  • dc.date.accessioned 2021-11-04T07:38:23Z
  • dc.date.available 2021-11-04T07:38:23Z
  • dc.date.issued 2020
  • dc.description.abstract In this issue, Kabbert et al. (https://doi.org/10.1084/jem.20200275) show that intestinal antibodies from healthy subjects or patients with Crohn's disease cross-target diverse but distinct communities of the gut microbiota through a mechanism involving somatic hypermutation but not germline-encoded polyreactivity.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Grasset EK, Cerutti A. Mutations make gut antibodies promiscuous. J Exp Med. 2020 Nov 2; 217(11): e20201340. DOI: 10.1084/jem.20201340
  • dc.identifier.doi http://dx.doi.org/10.1084/jem.20201340
  • dc.identifier.issn 0022-1007
  • dc.identifier.uri http://hdl.handle.net/10230/48899
  • dc.language.iso eng
  • dc.publisher Rockefeller University Press
  • dc.rights This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/)
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/4.0/
  • dc.subject.other Immunoglobulines
  • dc.subject.other Intestins--Microbiologia
  • dc.subject.other Crohn, Malaltia de
  • dc.title Mutations make gut antibodies promiscuous
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion