Testing the null hypothesis of the nonexistence of a preseizure state
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- dc.contributor.author Andrzejak, Ralph Gregor
- dc.contributor.author Mormann, Florian
- dc.contributor.author Kreuz, Thomas
- dc.contributor.author Rieke, Christoph
- dc.contributor.author Kraskov, Alexander
- dc.contributor.author Elger, Christian E.
- dc.contributor.author Lehnertz, Klaus
- dc.date.accessioned 2020-02-18T13:54:35Z
- dc.date.available 2020-02-18T13:54:35Z
- dc.date.issued 2003
- dc.description.abstract A rapidly growing number of studies deals with the prediction of epileptic seizures. For this purpose, various techniques derived from linear and nonlinear time series analysis have been applied to the electroencephalogram of epilepsy patients. In none of these works, however, the performance of the seizure prediction statistics is tested against a null hypothesis, an otherwise ubiquitous concept in science. In consequence, the evaluation of the reported performance values is problematic. Here, we propose the technique of seizure time surrogates based on a Monte Carlo simulation to remedy this deficit.en
- dc.description.sponsorship C.E.E., T.K., K.L., F.M., and C.R. acknowledge support from the Deutsche Forschungsgemeinschaft.
- dc.format.mimetype application/pdf
- dc.identifier.citation Andrzejak RG, Mormann F, Kreuz T, Rieke C, Kraskov A, Elger CE, Lehnertz K. Testing the null hypothesis of the nonexistence of a preseizure state. Phys Rev E. 2003;67:010901. DOI: 10.1103/PhysRevE.67.010901
- dc.identifier.doi http://dx.doi.org/10.1103/PhysRevE.67.010901
- dc.identifier.issn 2470-0045
- dc.identifier.uri http://hdl.handle.net/10230/43635
- dc.language.iso eng
- dc.publisher American Physical Society
- dc.relation.ispartof Physical Review E. 2003;67:010901
- dc.rights © American Physical Society. Published article available at dx.doi.org/10.1103/PhysRevE.67.010901
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Nonlinear signal analysisen
- dc.subject.keyword Electroencephalographic recordingsen
- dc.subject.keyword Epilepsyen
- dc.subject.keyword Seizure predictionen
- dc.subject.keyword Nonlinear signal analysisen
- dc.subject.keyword Electroencephalographic recordingsen
- dc.subject.keyword Epilepsyen
- dc.subject.keyword Seizure predictionen
- dc.title Testing the null hypothesis of the nonexistence of a preseizure stateen
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion