European Roma groups show complex West Eurasian admixture footprints and a common South Asian genetic origin
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- dc.contributor.author Font-Porterias, Neus
- dc.contributor.author Arauna, Lara R
- dc.contributor.author Poveda, Alaitz
- dc.contributor.author Bianco, Erica
- dc.contributor.author Rebato, Esther
- dc.contributor.author Prata, Maria Joao
- dc.contributor.author Calafell i Majó, Francesc
- dc.contributor.author Comas, David, 1969-
- dc.date.accessioned 2019-11-06T10:51:39Z
- dc.date.available 2019-11-06T10:51:39Z
- dc.date.issued 2019
- dc.description.abstract The Roma population is the largest transnational ethnic minority in Europe, characterized by a linguistic, cultural and historical heterogeneity. Comparative linguistics and genetic studies have placed the origin of European Roma in the Northwest of India. After their migration across Persia, they entered into the Balkan Peninsula, from where they spread into Europe, arriving in the Iberian Peninsula in the 15th century. Their particular demographic history has genetic implications linked to rare and common diseases. However, the South Asian source of the proto-Roma remains still untargeted and the West Eurasian Roma component has not been yet deeply characterized. Here, in order to describe both the South Asian and West Eurasian ancestries, we analyze previously published genome-wide data of 152 European Roma and 34 new Iberian Roma samples at a fine-scale and haplotype-based level, with special focus on the Iberian Roma genetic substructure. Our results suggest that the putative origin of the proto-Roma involves a Punjabi group with low levels of West Eurasian ancestry. In addition, we have identified a complex West Eurasian component (around 65%) in the Roma, as a result of the admixture events occurred with non-proto-Roma populations between 1270-1580. Particularly, we have detected the Balkan genetic footprint in all European Roma, and the Baltic and Iberian components in the Northern and Western Roma groups, respectively. Finally, our results show genetic substructure within the Iberian Roma, with different levels of West Eurasian admixture, as a result of the complex historical events occurred in the Peninsula.
- dc.format.mimetype application/pdf
- dc.identifier.citation Font-Porterias N, Arauna LR, Poveda A, Bianco E, Rebato E, Prata MJ et al. European Roma groups show complex West Eurasian admixture footprints and a common South Asian genetic origin. PLoS Genet. 2019;15(9):e1008417. DOI: 10.1371/journal.pgen.1008417
- dc.identifier.doi http://dx.doi.org/10.1371/journal.pgen.1008417
- dc.identifier.issn 1553-7390
- dc.identifier.uri http://hdl.handle.net/10230/42753
- dc.language.iso eng
- dc.publisher Public Library of Science (PLoS)
- dc.relation.ispartof PLOS Genetics. 2019;15(9):e1008417
- dc.rights © 2019 Font-Porterias et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Romani people
- dc.subject.keyword Europe
- dc.subject.keyword Autosomes
- dc.subject.keyword Population genetics
- dc.subject.keyword X chromosomes
- dc.subject.keyword India
- dc.subject.keyword Genetic footprinting
- dc.subject.keyword Gene flow
- dc.title European Roma groups show complex West Eurasian admixture footprints and a common South Asian genetic origin
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion