Use of traditional medicine and control of hypertension in 12 African countries

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  • dc.contributor.author Lassale, Camille
  • dc.contributor.author Jouven, Xavier
  • dc.date.accessioned 2022-10-11T07:13:39Z
  • dc.date.available 2022-10-11T07:13:39Z
  • dc.date.issued 2022
  • dc.description.abstract Background: use of traditional medicine (TM) is widespread in sub-Saharan Africa as a treatment option for a wide range of disease. We aimed to describe main characteristics of TM users and estimate the association of TM use with control of hypertension. Methods: we used data on 2128 hypertensive patients of a cross-sectional study (convenience sampling), who attended cardiology departments of 12 sub-Saharan African countries (Benin, Cameroon, Congo, Democratic Republic of the Congo, Gabon, Guinea, Côte d'Ivoire, Mauritania, Mozambique, Niger, Senegal, Togo). To model association of TM use with odds of uncontrolled, severe and complicated hypertension, we used multivariable mixed logistic regressions, and to model the association with blood pressure (systolic (SBP) and diastolic (DBP)) we used mixed linear models. All models were adjusted for age, sex, wealth, adherence to hypertension conventional treatment and country (random effect). Results: a total of 512 (24%) participants reported using TM, varying across countries from 10% in the Congo to 48% in Guinea. TM users were more likely to be men, living in rural area, poorly adhere to prescribed medication (frequently due to its cost). Use of TM was associated with a 3.87 (95% CI 1.52 to 6.22)/1.75 (0.34 to 3.16) mm Hg higher SBP/DBP compared with no use; and with greater odds of severe hypertension (OR=1.34; 95% CI 1.04 to 1.74) and of any hypertension complication (OR=1.27; 95% CI 1.01 to 1.60), mainly driven by renal complication (OR=1.57; 95% CI 1.07 to 2.29) after adjustment for measured confounders. Conclusions: the use of TM was associated with higher blood pressure, more severe hypertension and more complications in Sub-Saharan African countries. The widespread use of TM needs to be acknowledged and worked out to integrate TM safely within the conventional healthcare.
  • dc.description.sponsorship Camille Lassale is supported by a fellowship from 'La Caixa' Foundation (ID 100010434) and from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 847 648. The fellowship code is LCF/BQ/PR21/11840003. Bamba Gaye is supported by a Lefoulon Delalande grant and a Fondation Bettencourt Schueller Price. The EIGHT study is supported by INSERM (Institut national de la Santé et de la Recherche Médicale), AP-HP (Assistance Publique Hôpitaux de Paris), Paris Descartes University.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Lassale C, Gaye B, Diop IB, Mipinda JB, Kramoh KE, Kouam Kouam C, et al. Use of traditional medicine and control of hypertension in 12 African countries. BMJ Glob Health. 2022 Jun; 7(6): e008138. DOI: 10.1136/bmjgh-2021-008138
  • dc.identifier.doi http://dx.doi.org/10.1136/bmjgh-2021-008138
  • dc.identifier.issn 2059-7908
  • dc.identifier.uri http://hdl.handle.net/10230/54350
  • dc.language.iso eng
  • dc.publisher BMJ Publishing Group
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/847648
  • dc.rights Copyright © Lassale C, Gaye B, Diop IB, Mipinda JB, Kramoh KE, Kouam Kouam C, 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
  • dc.subject.keyword Epidemiology
  • dc.subject.keyword Hypertension
  • dc.title Use of traditional medicine and control of hypertension in 12 African countries
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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