The Y chromosome as the most popular marker in genetic genealogy benefits interdisciplinary research

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• dc.contributor.author Calafell i Majó, Francesc
• dc.contributor.author Larmuseau, Maarten H. D.
• dc.date.accessioned 2019-01-31T09:21:28Z
• dc.date.available 2019-01-31T09:21:28Z
• dc.date.issued 2017
• dc.description.abstract The Y chromosome is currently by far the most popular marker in genetic genealogy that combines genetic data and family history. This popularity is based on its haploid character and its close association with the patrilineage and paternal inherited surname. Other markers have not been found (yet) to overrule this status due to the low sensitivity and precision of autosomal DNA for genetic genealogical applications, given the vagaries of recombination, and the lower capacities of mitochondrial DNA combined with an in general much lower interest in maternal lineages. The current knowledge about the Y chromosome and the availability of markers with divergent mutation rates make it possible to answer questions on relatedness levels which differ in time depth; from the individual and familial level to the surnames, clan and population level. The use of the Y chromosome in genetic genealogy has led to applications in several well-established research disciplines; namely in, e.g., family history, demography, anthropology, forensic sciences, population genetics and sex chromosome evolution. The information obtained from analysing this chromosome is not only interesting for academic scientists but also for the huge and lively community of amateur genealogists and citizen-scientists, fascinated in analysing their own genealogy or surname. This popularity, however, has also some drawbacks, mainly for privacy reasons related to the DNA donor, his close family and far-related namesakes. In this review paper we argue why Y-chromosomal analysis and its genetic genealogical applications will still perform an important role in future interdisciplinary research.
• dc.format.mimetype application/pdf
• dc.identifier.citation Calafell F, Larmuseau MHD. The Y chromosome as the most popular marker in genetic genealogy benefits interdisciplinary research. Hum Genet. 2017;136(5):559-73. DOI: 10.1007/s00439-016-1740-0
• dc.identifier.doi http://dx.doi.org/10.1007/s00439-016-1740-0
• dc.identifier.issn 0340-6717
• dc.identifier.uri http://hdl.handle.net/10230/36464
• dc.language.iso eng
• dc.publisher Springer
• dc.relation.ispartof Human Genetics. 2017;136(5):559-73
• dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s00439-016-1740-0
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Paternal lineage
• dc.subject.keyword Descent group
• dc.subject.keyword Genetic genealogy
• dc.subject.keyword False paternity
• dc.subject.keyword Paternal ancestor
• dc.title The Y chromosome as the most popular marker in genetic genealogy benefits interdisciplinary research
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion