Single-cell transcriptional changes in neurodegenerative diseases
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- dc.contributor.author Ahmadi, Amirhossein
- dc.contributor.author Gispert López, Juan Domingo
- dc.contributor.author Navarro i Cuartiellas, Arcadi, 1969-
- dc.contributor.author Vilor Tejedor, Natàlia, 1988-
- dc.contributor.author Sadeghi, Iman
- dc.date.accessioned 2021-12-15T07:30:38Z
- dc.date.available 2021-12-15T07:30:38Z
- dc.date.issued 2021
- dc.description.abstract In recent decades, our understanding of the molecular changes involved in neurodegenerative diseases has been transformed. Single-cell RNA sequencing and single-nucleus RNA sequencing technologies have been applied to provide cellular and molecular details of the brain at the single-cell level. This has expanded our knowledge of the central nervous system and provided insights into the molecular vulnerability of brain cell types and underlying mechanisms in neurodegenerative diseases. In this review, we highlight the recent advances and findings related to neurodegenerative diseases using these cutting-edge technologies.
- dc.format.mimetype application/pdf
- dc.identifier.citation Ahmadi A, Gispert JD, Navarro A, Vilor-Tejedor N, Sadeghi I. Single-cell transcriptional changes in neurodegenerative diseases. Neuroscience. 2021;479:192-205. DOI: 10.1016/j.neuroscience.2021.10.025
- dc.identifier.doi http://dx.doi.org/10.1016/j.neuroscience.2021.10.025
- dc.identifier.issn 0306-4522
- dc.identifier.uri http://hdl.handle.net/10230/49214
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Neuroscience. 2021;479:192-205
- dc.rights © 2021 The Author(s). Published by Elsevier Ltd on behalf of IBRO. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
- dc.subject.keyword Alzheimer’s
- dc.subject.keyword Huntington
- dc.subject.keyword Parkinson
- dc.subject.keyword Multiple sclerosis
- dc.subject.keyword Neurodegenerative disease
- dc.subject.keyword Single-cell RNA sequencing
- dc.title Single-cell transcriptional changes in neurodegenerative diseases
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion