Environmental exposure assessment in European birth cohorts: results from the ENRIECO project

Gehring, Ulrike; Casas Sanahuja, Maribel; Brunekreef, Bert; Bergström, Anna; Bonde, Jens Peter; Botton, Jérémie; Chévrier, Cecile; Cordier, Sylvaine; Heinrich, Joachim; Hohmann, Cynthia; Keil, Thomas; Sunyer Deu, Jordi; Tischer, Christina; Toft, Gunnar; Wickman, Magnus; Vrijheid, Martine; Nieuwenhuijsen, Mark J.

Environmental exposure assessment in European birth cohorts: results from the ENRIECO project

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dc.contributor.author Gehring, Ulrikeca
dc.contributor.author Casas Sanahuja, Maribelca
dc.contributor.author Brunekreef, Bertca
dc.contributor.author Bergström, Annaca
dc.contributor.author Bonde, Jens Peterca
dc.contributor.author Botton, Jérémieca
dc.contributor.author Chévrier, Cecileca
dc.contributor.author Cordier, Sylvaineca
dc.contributor.author Heinrich, Joachimca
dc.contributor.author Hohmann, Cynthiaca
dc.contributor.author Keil, Thomasca
dc.contributor.author Sunyer Deu, Jordica
dc.contributor.author Tischer, Christinaca
dc.contributor.author Toft, Gunnarca
dc.contributor.author Wickman, Magnusca
dc.contributor.author Vrijheid, Martineca
dc.contributor.author Nieuwenhuijsen, Mark J.ca
dc.date.accessioned 2015-03-16T08:16:21Z
dc.date.available 2015-03-16T08:16:21Z
dc.date.issued 2013ca
dc.description.abstract Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.en
dc.description.sponsorship This work was supported by ENRIECO (Environmental Health Risks in European Birth Cohorts), a project conducted within the European Union's 7th Framework Programme (Theme 6, Environment (Including Climate Change)) [Grant agreement number: 226285]en
dc.format.mimetype application/pdfca
dc.identifier.citation Gehring U, Casas M, Brunekreef B, Bergström A, Bonde JP, Botton J et al. Environmental exposure assessment in European birth cohorts: results from the ENRIECO project. Environmental Health. 2013; 12: 8. DOI 10.1186/1476-069X-12-8ca
dc.identifier.doi http://dx.doi.org/10.1186/1476-069X-12-8
dc.identifier.issn 1476-069Xca
dc.identifier.uri http://hdl.handle.net/10230/23186
dc.language.iso engca
dc.publisher BioMed Centralca
dc.relation.ispartof Environmental Health. 2013; 12: 8
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/226285ca
dc.rights © 2013 Gehring et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.ca
dc.rights.accessRights info:eu-repo/semantics/openAccessca
dc.rights.uri http://creativecommons.org/licenses/by/2.0
dc.subject.keyword Environmenten
dc.subject.keyword Europeen
dc.subject.keyword Exposure assessmenten
dc.subject.keyword Birth cohorten
dc.subject.keyword Reviewen
dc.subject.other Embaràsca
dc.subject.other Salut ambientalca
dc.title Environmental exposure assessment in European birth cohorts: results from the ENRIECO projectca
dc.type info:eu-repo/semantics/articleca
dc.type.version info:eu-repo/semantics/publishedVersionca

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