Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional study

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• dc.contributor.author Guiriguet, Carolinaca
• dc.contributor.author Pera, Guillemca
• dc.contributor.author Castells, Antonica
• dc.contributor.author Toran, Pereca
• dc.contributor.author Grau, Jaumeca
• dc.contributor.author Rivero, Ireneca
• dc.contributor.author Buron Pust, Andreaca
• dc.contributor.author Macià Guilà, Francesc Assísca
• dc.contributor.author Vela-Vallespín, Carmenca
• dc.contributor.author Vilarrubí-Estrella, Mercedesca
• dc.contributor.author Marzo-Castillejo Mercedesca
• dc.date.accessioned 2018-04-12T07:24:19Z
• dc.date.available 2018-04-12T07:24:19Z
• dc.date.issued 2017
• dc.description.abstract BACKGROUND: There is controversy regarding how comorbidity impacts on colorectal cancer screening, especially in the context of organised programmes. The aim of this study is to assess the effect of comorbidities on participation in the Barcelona population-based colorectal cancer screening programme (BCCSP). METHODS: Cross-sectional study carried out in ten primary care centres involved in the BCCSP. Individuals aged 50 to 69, at average risk of colorectal cancer, who were invited to participate in the first round of the faecal immunochemical test-based BCCSP were included (2011-2012). The main variable was participation in the BCCSP. Comorbidity was assessed by clinical risk group status. Other adjusting variables were age, sex, socioeconomic deprivation, visits to primary care, smoking, alcohol consumption and body mass index. Logistic regression models were used to test the association between participation in the programme and potential explanatory variables. The results were given as incidence rate ratios (IRR) and their 95% confidence intervals (CI). RESULTS: Of the 36,208 individuals included, 17,404 (48%) participated in the BCCSP. Participation was statistically significantly higher in women, individuals aged 60 to 64, patients with intermediate socioeconomic deprivation, and patients with more medical visits. There was a higher rate of current smoking, high-risk alcohol intake, obesity and individuals in the highest comorbidity categories in the non-participation group. In the adjusted analysis, only individuals with multiple minor chronic diseases were more likely to participate in the BCCSP (IRR 1.14; 95% CI [1.06 to 1.22]; p < 0.001). In contrast, having three or more dominant chronic diseases was associated with lower participation in the screening programme (IRR 0.76; 95% CI [0.65 to 0.89]; p = 0.001). CONCLUSIONS: Having three or more dominant chronic diseases, was associated with lower participation in a faecal immunochemical test-based colorectal cancer screening programme, whereas individuals with multiple minor chronic diseases were more likely to participate. Further research is needed to explore comorbidity as a cause of non-participation in colorectal cancer screening programmes and which individuals could benefit most from colorectal cancer screening.
• dc.format.mimetype application/pdf
• dc.identifier.citation Guiriguet C, Pera G, Castells A, Toran P, Grau J, Rivero I. et al. Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional study. BMC Cancer. 2017 Aug 7;17(1):524. DOI: 10.1186/s12885-017-3516-x
• dc.identifier.doi http://dx.doi.org/10.1186/s12885-017-3516-x
• dc.identifier.issn 1471-2407
• dc.identifier.uri http://hdl.handle.net/10230/34342
• dc.language.iso eng
• dc.publisher BioMed Centralca
• dc.rights Copyright © The Author(s). 2017. Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Chronic disease
• dc.subject.keyword Colorectal neoplasm
• dc.subject.keyword Comorbidity
• dc.subject.keyword Early detection of cancer
• dc.subject.keyword Mass screening
• dc.subject.keyword Primary health care
• dc.subject.keyword Public health
• dc.subject.other Salut pública
• dc.subject.other Còlon -- Càncer -- Prevenció
• dc.subject.other Atenció primària -- Catalunya -- Barcelona
• dc.title Impact of comorbid conditions on participation in an organised colorectal cancer screening programme: a cross-sectional studyca
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion