Congenericity of claimed compounds in patent applications

Falaguera Mata, Maria José, 1994-; Mestres i López, Jordi

doi:http://dx.doi.org/10.3390/molecules26175253

Congenericity of claimed compounds in patent applications

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Falaguera MJ, Mestres J. Congenericity of claimed compounds in patent applications. Molecules. 2021 Aug 30; 26(17):5253. DOI: 10.3390/molecules26175253

Abstract

A method is presented to analyze quantitatively the degree of congenericity of claimed compounds in patent applications. The approach successfully differentiates patents exemplified with highly congeneric compounds of a structurally compact and well defined chemical series from patents containing a more diverse set of compounds around a more vaguely described patent claim. An application to 750 common patents available in SureChEMBL, SureChEMBLccs and ChEMBL is presented and the congenericity of patent compounds in those different sources discussed.