Y-chromosome analysis in individuals bearing the Basarab name of the first dynasty of Wallachian kings

Martínez Cruz, Begoña; Ioana, Mihai; Calafell i Majó, Francesc; Arauna, Lara R; Sanz, Paula; Ionescu, Ramona; Boengiu, Sandu; Kalaydjieva, Luba; Pamjav, Horolma; Makukh, Halyna; Plantinga, Theo; van der Meer, Jos W.M.; Comas, David, 1969-; Netea, Mihai G

Y-chromosome analysis in individuals bearing the Basarab name of the first dynasty of Wallachian kings

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dc.contributor.author Martínez Cruz, Begoñaca
dc.contributor.author Ioana, Mihaica
dc.contributor.author Calafell i Majó, Francescca
dc.contributor.author Arauna, Lara Rca
dc.contributor.author Sanz, Paulaca
dc.contributor.author Ionescu, Ramonaca
dc.contributor.author Boengiu, Sanduca
dc.contributor.author Kalaydjieva, Lubaca
dc.contributor.author Pamjav, Horolmaca
dc.contributor.author Makukh, Halynaca
dc.contributor.author Plantinga, Theoca
dc.contributor.author van der Meer, Jos W.M.ca
dc.contributor.author Comas, David, 1969-ca
dc.contributor.author Netea, Mihai Gca
dc.date.accessioned 2015-05-11T11:49:09Z
dc.date.available 2015-05-11T11:49:09Z
dc.date.issued 2012ca
dc.description.abstract Vlad III The Impaler, also known as Dracula, descended from the dynasty of Basarab, the first rulers of independent Wallachia, in present Romania. Whether this dynasty is of Cuman (an admixed Turkic people that reached Wallachia from the East in the 11th century) or of local Romanian (Vlach) origin is debated among historians. Earlier studies have demonstrated the value of investigating the Y chromosome of men bearing a historical name, in order to identify their genetic origin. We sampled 29 Romanian men carrying the surname Basarab, in addition to four Romanian populations (from counties Dolj, N = 38; Mehedinti, N = 11; Cluj, N = 50; and Brasov, N = 50), and compared the data with the surrounding populations. We typed 131 SNPs and 19 STRs in the non-recombinant part of the Y-chromosome in all the individuals. We computed a PCA to situate the Basarab individuals in the context of Romania and its neighboring populations. Different Y-chromosome haplogroups were found within the individuals bearing the Basarab name. All haplogroups are common in Romania and other Central and Eastern European populations. In a PCA, the Basarab group clusters within other Romanian populations. We found several clusters of Basarab individuals having a common ancestor within the period of the last 600 years. The diversity of haplogroups found shows that not all individuals carrying the surname Basarab can be direct biological descendants of the Basarab dynasty. The absence of Eastern Asian lineages in the Basarab men can be interpreted as a lack of evidence for a Cuman origin of the Basarab dynasty, although it cannot be positively ruled out. It can be therefore concluded that the Basarab dynasty was successful in spreading its name beyond the spread of its genes.en
dc.description.sponsorship The present study was supported by the Ministerio de Ciencia e Innovación, Spain (CGL2010-14944), Direcció General de Recerca, Generalitat de Catalunya (2009SGR1101) (both to DC), and a Vici Grant of the Netherlands Organization for Scientific Research (to MGN).en
dc.format.mimetype application/pdfca
dc.identifier.citation Martínez-Cruz B, Ioana M, Calafell F, Arauna LR, Sanz P, Ionescu R et al. Y-chromosome analysis in individuals bearing the Basarab name of the first dynasty of Wallachian kings. PLoS ONE. 2012;7(7):e41803. DOI: 10.1371/journal.pone.0041803ca
dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0041803
dc.identifier.issn 1932-6203ca
dc.identifier.uri http://hdl.handle.net/10230/23543
dc.language.iso engca
dc.publisher Public Library of Science (PLoS)ca
dc.relation.ispartof PLoS ONE. 2012;7(7):e41803
dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/CGL2010-14944
dc.rights © 2012 Martinez-Cruz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ca
dc.rights.accessRights info:eu-repo/semantics/openAccessca
dc.subject.other Cromosoma Yca
dc.subject.other Genètica de poblacions humanesca
dc.subject.other Romania -- Poblacióca
dc.title Y-chromosome analysis in individuals bearing the Basarab name of the first dynasty of Wallachian kingsen
dc.type info:eu-repo/semantics/articleca
dc.type.version info:eu-repo/semantics/publishedVersionca

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