RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12

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• dc.contributor.author Salgado, Heladia
• dc.contributor.author Gelpí, Josep Lluís
• dc.contributor.author Collado Vides, Pedro Julio
• dc.date.accessioned 2024-02-14T10:58:07Z
• dc.date.available 2024-02-14T10:58:07Z
• dc.date.issued 2024
• dc.description.abstract RegulonDB is a database that contains the most comprehensive corpus of knowledge of the regulation of transcription initiation of Escherichia coli K-12, including data from both classical molecular biology and high-throughput methodologies. Here, we describe biological advances since our last NAR paper of 2019. We explain the changes to satisfy FAIR requirements. We also present a full reconstruction of the RegulonDB computational infrastructure, which has significantly improved data storage, retrieval and accessibility and thus supports a more intuitive and user-friendly experience. The integration of graphical tools provides clear visual representations of genetic regulation data, facilitating data interpretation and knowledge integration. RegulonDB version 12.0 can be accessed at https://regulondb.ccg.unam.mx.
• dc.format.mimetype application/pdf
• dc.identifier.citation Salgado H, Gama-Castro S, Lara P, Mejia-Almonte C, Alarcón-Carranza G, López-Almazo AG et al. RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12. Nucleic Acids Res. 2024 Jan 5;52(D1):D255-64. DOI: 10.1093/nar/gkad1072
• dc.identifier.doi http://dx.doi.org/10.1093/nar/gkad1072
• dc.identifier.issn 0305-1048
• dc.identifier.uri http://hdl.handle.net/10230/59107
• dc.language.iso eng
• dc.publisher Oxford University Press
• dc.relation.ispartof Nucleic Acids Res. 2024 Jan 5;52(D1):D255-64
• dc.rights © The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
• dc.subject.other Biologia molecular
• dc.subject.other Regulació genètica
• dc.title RegulonDB v12.0: a comprehensive resource of transcriptional regulation in E. coli K-12
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion