Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions.

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• dc.contributor.author González, Déboraca
• dc.contributor.author Torrens, Martaca
• dc.contributor.author Farré Albaladejo, Magíca
• dc.date.accessioned 2016-02-09T12:12:24Z
• dc.date.available 2016-02-09T12:12:24Z
• dc.date.issued 2015
• dc.description.abstract BACKGROUND: 2C-B (Nexus) is one of the most widespread novel psychoactive substances. There is limited information about its pharmacological properties, and few studies in humans concern its acute and chronic effects. 2C-B has been classified as a stimulant, hallucinogen, entactogen, and/or empathogen. OBJECTIVES: To evaluate the emotional, subjective, and cardiovascular effects of 2C-B. METHODS: Twenty healthy recreational 2C-B users (12 women) self-administered a 20 mg dose of 2C-B. Evaluations included emotional (IAPS, FERT, and speech), subjective (visual analog scales, ARCI, VESSPA, HRS, and POMS questionnaires), and cardiovascular effects (blood pressure and heart rate). Results. Positive subjective effects predominated with a reduction of anger under the influence of 2C-B. It did, however, increase reactivity to negative emotional stimuli and decrease the ability to recognize expressions of happiness. Augmented emotionality in speech could be appreciated by others. 2C-B induced euphoria and well-being, changes in perceptions, and slight hallucinogenic states. Mild sympathetic actions were observed./nCONCLUSIONS: The specific profile that 2C-B exerts on emotions suggests its classification as an entactogen with psychedelic properties.ca
• dc.description.sponsorship The paper was supported by grants from Ministerio de Sanidad, Políıtica Social e Igualdad (Plan Nacional sobre Drogas, 2009I047), Ministerio de Economía y Competitividad Instituto de Salud Carlos III (Red de Trastornos Adictivos, UE-FEDER 2012, RD12/0028/0009, and FIS-FEDER, FIS PI11/01961) and The European Commission (Drug Prevention and Information Programme 2014-16, Contract no. JUST/2013/DPIP/AG/4823, EU-MADNESS project).
• dc.format.mimetype application/pdfca
• dc.identifier.citation González D, Torrens M, Farré M. Acute effects of the novel psychoactive drug 2C-B on emotions. Biomed Res Int. 2015;2015:643878. doi: 10.1155/2015/643878.ca
• dc.identifier.doi http://dx.doi.org/10.1155/2015/643878
• dc.identifier.issn 2314-6133
• dc.identifier.uri http://hdl.handle.net/10230/25759
• dc.language.iso engca
• dc.publisher Hindawi Publishing Corporationca
• dc.relation.ispartof BioMed Research International. 2015;2015:643878
• dc.rights © 2015 Débora González et al. This is an open access article distributed under the http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.rights.uri http://creativecommons.org/licenses/by/3.0/ca
• dc.subject.other Medicaments -- Efectes secundarisca
• dc.title Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions.ca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/publishedVersionca