MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
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- dc.contributor.author Wodke, Judith A.H.ca
- dc.contributor.author Alibés, Andreuca
- dc.contributor.author Cozzuto, Lucaca
- dc.contributor.author Hermoso Pulido, Antonioca
- dc.contributor.author Yus, Evaca
- dc.contributor.author Lluch-Senar, Maria 1982-ca
- dc.contributor.author Serrano Pubull, Luis, 1982-ca
- dc.contributor.author Roma, Guglielmoca
- dc.date.accessioned 2015-11-17T14:35:55Z
- dc.date.available 2015-11-17T14:35:55Z
- dc.date.issued 2015
- dc.description.abstract MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is an interesting model organisms for the development of systems biology approaches for unicellular organisms. Our database hosts a wealth of omics-scale datasets generated by hundreds of experimental and computational analyses. These include data obtained from gene expression profiling experiments, gene essentiality studies, protein abundance profiling, protein complex analysis, metabolic reactions and network modeling, cell growth experiments, comparative genomics and 3D tomography. In addition, the intuitive web interface provides access to several visualization and analysis tools as well as to different data search options. The availability and--even more relevant--the accessibility of properly structured and organized data are of up-most importance when aiming to understand the biology of an organism on a global scale. Therefore, MyMpn constitutes a unique and valuable new resource for the large systems biology and microbiology community.en
- dc.description.sponsorship European Union through the European Research Council (ERC) [‘Celldoctor’ GA 232913]; Spanish Ministerio de Economía y Competitividad Plan Nacional [BIO2007-61762]; Fundaci´on Marcelino Botin [to L.S.]. laCaixa-CRG Fellowship, Fundació laCaixa [to J.W.]; Spanish Ministry of Economy and Competitiveness No [PTA2010-4446-I to A.H.; PTA2011-6729-I to L.C.]. Funding for open access charge: ERC [to L.S.].en
- dc.format.mimetype application/pdfca
- dc.identifier.citation Wodke JA, Alibés A, Cozzuto L, Hermoso A, Yus E, Lluch-Senar M et al. MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae. Nucleic acids research. 2015; 43: D618-D623. DOI 10.1093/nar/gku1105en
- dc.identifier.doi http://dx.doi.org/10.1093/nar/gku1105
- dc.identifier.issn 0305-1048
- dc.identifier.uri http://hdl.handle.net/10230/25116
- dc.language.iso engca
- dc.publisher Oxford University Pressca
- dc.relation.ispartof Nucleic acids research. 2015; 43: D618-D623
- dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/232913
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PN/BIO2007-61762
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PTA2010-4446
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/PTA2011-6729
- dc.rights © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. this is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.en
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/ca
- dc.subject.other Mycoplasma pneumoniae -- Aspectes genètics
- dc.subject.other Mycoplasma pneumoniae -- Metabolisme
- dc.subject.other Genètica bacteriana
- dc.subject.other Genomes bacterians
- dc.subject.other Bases de dades
- dc.title MyMpn: a database for the systems biology model organism Mycoplasma pneumoniaeen
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/acceptedVersionca